The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

ICE1  -  transcription factor ICE1

Arabidopsis thaliana

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on ICE1


Biological context of ICE1


Regulatory relationships of ICE1

  • The ice1 mutation blocks the expression of CBF3 and decreases the expression of many genes downstream of CBFs, which leads to a significant reduction in plant chilling and freezing tolerance [1].

Other interactions of ICE1

  • Our results indicate that cold stress responses in Arabidopsis are attenuated by a ubiquitination/proteasome pathway in which HOS1 mediates the degradation of the ICE1 protein [2].


  1. ICE1: a regulator of cold-induced transcriptome and freezing tolerance in Arabidopsis. Chinnusamy, V., Ohta, M., Kanrar, S., Lee, B.H., Hong, X., Agarwal, M., Zhu, J.K. Genes Dev. (2003) [Pubmed]
  2. The negative regulator of plant cold responses, HOS1, is a RING E3 ligase that mediates the ubiquitination and degradation of ICE1. Dong, C.H., Agarwal, M., Zhang, Y., Xie, Q., Zhu, J.K. Proc. Natl. Acad. Sci. U.S.A. (2006) [Pubmed]
  3. Mapping of barley homologs to genes that regulate low temperature tolerance in Arabidopsis. Skinner, J.S., Szucs, P., von Zitzewitz, J., Marquez-Cedillo, L., Filichkin, T., Stockinger, E.J., Thomashow, M.F., Chen, T.H., Hayes, P.M. Theor. Appl. Genet. (2006) [Pubmed]
WikiGenes - Universities