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Gene Review

AKAP17A  -  A kinase (PRKA) anchor protein 17A

Homo sapiens

Synonyms: 721P, A-kinase anchor protein 17A, AKAP-17A, B-lymphocyte antigen, CCDC133, ...
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Disease relevance of CXYorf3

  • Two gaps of less than 50 kb within the genomic locus of CSF2RA and around XE7 remain, which could not be covered with YACs, cosmids, or phages [1].

High impact information on CXYorf3


Anatomical context of CXYorf3

  • XE7 had been identified in a large-scale proteomic analysis of the human spliceosome [4].


  1. Characterization of a YAC contig spanning the pseudoautosomal region. Ried, K., Mertz, A., Nagaraja, R., Trusgnich, M., Riley, J.H., Anand, R., Lehrach, H., Page, D., Ellison, J.W., Rappold, G. Genomics (1995) [Pubmed]
  2. Cloning and sequencing of a trophoblast-endothelial-activated lymphocyte surface protein: cDNA sequence and genomic structure. Voland, J.R., Wyzykowski, R.J., Huang, M., Dutton, R.W. Proc. Natl. Acad. Sci. U.S.A. (1992) [Pubmed]
  3. Gene duplications as a recurrent theme in the evolution of the human pseudoautosomal region 1: isolation of the gene ASMTL. Ried, K., Rao, E., Schiebel, K., Rappold, G.A. Hum. Mol. Genet. (1998) [Pubmed]
  4. XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265. Mangs, A.H., Speirs, H.J., Goy, C., Adams, D.J., Markus, M.A., Morris, B.J. Nucleic Acids Res. (2006) [Pubmed]
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