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Gene Review

IAA14  -  auxin-responsive protein IAA14

Arabidopsis thaliana

Synonyms: DL3315C, FCAALL.254, SLR, SOLITARY ROOT, indole-3-acetic acid inducible 14
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High impact information on IAA14


Biological context of IAA14

  • We showed that plants expressing the mIAA14-glucocorticoid receptor (GR) fusion protein under the control of the native IAA14 promoter had the solitary-root/iaa14 mutant phenotypes, including the lack of LR formation under dexamethasone (Dex) treatment, indicating that mIAA14-GR is functional in the presence of Dex [5].
  • Green fluorescent protein-tagged mutant IAA14 protein was localized in the nucleus, and the gain-of-function slr-1/iaa14 mutation decreased auxin-inducible BA-GUS gene expression in the root, suggesting that SLR/IAA14 acts as a transcriptional repressor [6].
  • These observations indicate that SLR/IAA14 is a key regulator in auxin-regulated growth and development, particularly in lateral root formation [6].
  • These results indicate that the product of the SLR1 gene is an intermediate of the GA signal transduction pathway [3].

Associations of IAA14 with chemical compounds

  • Interestingly, key components of the cell cycle machinery were strongly defective in slr1, suggesting a direct link between AUX/IAA signaling and core cell cycle regulation [1].


  1. Cell cycle progression in the pericycle is not sufficient for SOLITARY ROOT/IAA14-mediated lateral root initiation in Arabidopsis thaliana. Vanneste, S., De Rybel, B., Beemster, G.T., Ljung, K., De Smet, I., Van Isterdael, G., Naudts, M., Iida, R., Gruissem, W., Tasaka, M., Inzé, D., Fukaki, H., Beeckman, T. Plant Cell (2005) [Pubmed]
  2. Foolish seedlings and DELLA regulators: the functions of rice SLR1 and Arabidopsis RGL1 in GA signal transduction. Eckardt, N.A. Plant Cell (2002) [Pubmed]
  3. slender rice, a constitutive gibberellin response mutant, is caused by a null mutation of the SLR1 gene, an ortholog of the height-regulating gene GAI/RGA/RHT/D8. Ikeda, A., Ueguchi-Tanaka, M., Sonoda, Y., Kitano, H., Koshioka, M., Futsuhara, Y., Matsuoka, M., Yamaguchi, J. Plant Cell (2001) [Pubmed]
  4. PICKLE is required for SOLITARY-ROOT/IAA14-mediated repression of ARF7 and ARF19 activity during Arabidopsis lateral root initiation. Fukaki, H., Taniguchi, N., Tasaka, M. Plant J. (2006) [Pubmed]
  5. Tissue-specific expression of stabilized SOLITARY-ROOT/IAA14 alters lateral root development in Arabidopsis. Fukaki, H., Nakao, Y., Okushima, Y., Theologis, A., Tasaka, M. Plant J. (2005) [Pubmed]
  6. Lateral root formation is blocked by a gain-of-function mutation in the SOLITARY-ROOT/IAA14 gene of Arabidopsis. Fukaki, H., Tameda, S., Masuda, H., Tasaka, M. Plant J. (2002) [Pubmed]
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