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Gene Review:

PRL1 - protein pleiotropic regulatory locus 1

Arabidopsis thaliana

Synonyms: DL3990W, FCAALL.40, PRL1 PROTEIN, pleiotropic regulatory locus 1

Bhalerao, R.P. et al., Salchert, K. et al.

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Disease relevance of PRL1

Mutation of the PRL1 gene, encoding a regulatory WD protein, results in glucose hypersensitivity and derepression of glucose-regulated genes in Arabidopsis [1].

High impact information on PRL1

This conclusion is supported by the observation that PRL1 is an inhibitor of AKIN10 and AKIN11 in vitro [1].
The prl1 mutation results in cell elongation defects, de-repression of numerous stress-induced genes, and augments the sensitivity of plants to glucose, cold stress and several hormones, including cytokinin, ethylene, auxin, and abscisic acid [2].

References

Regulatory interaction of PRL1 WD protein with Arabidopsis SNF1-like protein kinases. Bhalerao, R.P., Salchert, K., Bakó, L., Okrész, L., Szabados, L., Muranaka, T., Machida, Y., Schell, J., Koncz, C. Proc. Natl. Acad. Sci. U.S.A. (1999) [Pubmed]
Control of cell elongation and stress responses by steroid hormones and carbon catabolic repression in plants. Salchert, K., Bhalerao, R., Koncz-Kálmán, Z., Koncz, C. Philos. Trans. R. Soc. Lond., B, Biol. Sci. (1998) [Pubmed]

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