Disease relevance of ABF3/DPBF5

• The constitutive overexpression of ABF3 or ABF4 in Arabidopsis resulted in ABA hypersensitivity and other ABA-associated phenotypes [1].

High impact information on ABF3/DPBF5

• Here we report that the ABRE binding factors ABF3 and ABF4 function in ABA signaling [1].
• Arabidopsis CBF3/DREB1A and ABF3 in transgenic rice increased tolerance to abiotic stress without stunting growth [2].
• Although ABI5, ABF3, and ABF1 have some overlapping effects, they appear to antagonistically regulate each other's expression at specific stages [3].
• The abf1 and abf3 monogenic mutant lines had at most minimal effects on germination or seed-specific gene expression, but the enhanced ABA- and stress-resistance of abf3 abi5 double mutants revealed redundant action of these genes in multiple stress responses of seeds and seedlings [3].

Biological context of ABF3/DPBF5

• By using the 60 K Rice Whole Genome Microarray and RNA gel-blot analyses, we identified 12 and 7 target genes that were activated in transgenic rice plants by CBF3 and ABF3, respectively, which appear to render the corresponding plants acclimated for stress conditions [2].

Other interactions of ABF3/DPBF5

• Furthermore, the temporal and spatial expression patterns of ABF3 and ABF4 were consistent with their suggested roles [1].

References