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Gene Review:

BEL1 - homeobox protein BEL1

Arabidopsis thaliana

Synonyms: BELL 1, MYC6.12, MYC6_12

Kanrar, S. et al., Ray, A. et al., Reiser, L. et al., Balasubramanian, S. et al., Western, T.L. et al.

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High impact information on BEL1

Cloning of the BEL1 locus reveals that it encodes a homeodomain transcription factor [1].
Therefore, proximal-distal patterning of the ovule involves the regulated expression of the BEL1 gene that controls integument morphogenesis [1].
Arabidopsis floral homeotic gene BELL (BEL1) controls ovule development through negative regulation of AGAMOUS gene (AG) [2].
Introduction of a constitutively expressed AG transgene into wild-type plants causes the ovules to resemble those of bel1 mutants [2].
In addition, we show that NOZZLE and AINTEGUMENTA, which encodes an AP2 domain transcription factor, regulate the temporal expression of INNER NO OUTER and that BELL1 is essential for INNER NO OUTER expression [3].

Biological context of BEL1

Development of the abnormal integuments characteristic of the Bel1- mutant phenotype was found to be dependent on AG function [4].

Other interactions of BEL1

In Arabidopsis, two paralogous BEL1-like (BELL) homeobox genes, PENNYWISE (PNY) and POUND-FOOLISH (PNF), expressed in the SAM, encode DNA-binding proteins that are essential for specifying floral primordia and establishing early internode patterning events during inflorescence development [5].

References

The BELL1 gene encodes a homeodomain protein involved in pattern formation in the Arabidopsis ovule primordium. Reiser, L., Modrusan, Z., Margossian, L., Samach, A., Ohad, N., Haughn, G.W., Fischer, R.L. Cell (1995) [Pubmed]
Arabidopsis floral homeotic gene BELL (BEL1) controls ovule development through negative regulation of AGAMOUS gene (AG). Ray, A., Robinson-Beers, K., Ray, S., Baker, S.C., Lang, J.D., Preuss, D., Milligan, S.B., Gasser, C.S. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
NOZZLE links proximal-distal and adaxial-abaxial pattern formation during ovule development in Arabidopsis thaliana. Balasubramanian, S., Schneitz, K. Development (2002) [Pubmed]
BELL1 and AGAMOUS genes promote ovule identity in Arabidopsis thaliana. Western, T.L., Haughn, G.W. Plant J. (1999) [Pubmed]
Arabidopsis inflorescence architecture requires the activities of KNOX-BELL homeodomain heterodimers. Kanrar, S., Onguka, O., Smith, H.M. Planta (2006) [Pubmed]

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Os03g0124000	Oryza sativa Japonica Group
Os10g0534900	Oryza sativa Japonica Group
Os06g0108900	Oryza sativa Japonica Group

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