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Gene Review

XRN4  -  5'-3' exoribonuclease 4

Arabidopsis thaliana

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High impact information on AIN1


Biological context of AIN1

  • When both XRN4 and the RdRp were mutated, the plants accumulated decapped transgene mRNA [2].

Other interactions of AIN1

  • Here, we show that RdRp-dependent transgene silencing in Arabidopsis was caused by mutation of XRN4, which is a ribonuclease (RNase) implicated in mRNA turnover by means of decapping and 5'-3' exonucleolysis [2].


  1. The Exoribonuclease XRN4 Is a Component of the Ethylene Response Pathway in Arabidopsis. Potuschak, T., Vansiri, A., Binder, B.M., Lechner, E., Vierstra, R.D., Genschik, P. Plant Cell (2006) [Pubmed]
  2. A link between mRNA turnover and RNA interference in Arabidopsis. Gazzani, S., Lawrenson, T., Woodward, C., Headon, D., Sablowski, R. Science (2004) [Pubmed]
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