Gene Review:
CUL4B - cullin 4B
Homo sapiens
Synonyms:
CUL-4B, Cullin-4B, KIAA0695, MRXHF2, MRXS15, ...
- Mutations in CUL4B, Which Encodes a Ubiquitin E3 Ligase Subunit, Cause an X-linked Mental Retardation Syndrome Associated with Aggressive Outbursts, Seizures, Relative Macrocephaly, Central Obesity, Hypogonadism, Pes Cavus, and Tremor. Tarpey, P.S., Raymond, F.L., O'meara, S., Edkins, S., Teague, J., Butler, A., Dicks, E., Stevens, C., Tofts, C., Avis, T., Barthorpe, S., Buck, G., Cole, J., Gray, K., Halliday, K., Harrison, R., Hills, K., Jenkinson, A., Jones, D., Menzies, A., Mironenko, T., Perry, J., Raine, K., Richardson, D., Shepherd, R., Small, A., Varian, J., West, S., Widaa, S., Mallya, U., Moon, J., Luo, Y., Holder, S., Smithson, S.F., Hurst, J.A., Clayton-Smith, J., Kerr, B., Boyle, J., Shaw, M., Vandeleur, L., Rodriguez, J., Slaugh, R., Easton, D.F., Wooster, R., Bobrow, M., Srivastava, A.K., Stevenson, R.E., Schwartz, C.E., Turner, G., Gecz, J., Futreal, P.A., Stratton, M.R., Partington, M. Am. J. Hum. Genet. (2007)
- Mutation in CUL4B, Which Encodes a Member of Cullin-RING Ubiquitin Ligase Complex, Causes X-Linked Mental Retardation. Zou, Y., Liu, Q., Chen, B., Zhang, X., Guo, C., Zhou, H., Li, J., Gao, G., Guo, Y., Yan, C., Wei, J., Shao, C., Gong, Y. Am. J. Hum. Genet. (2007)
- Dioxin receptor is a ligand-dependent E3 ubiquitin ligase. Ohtake, F., Baba, A., Takada, I., Okada, M., Iwasaki, K., Miki, H., Takahashi, S., Kouzmenko, A., Nohara, K., Chiba, T., Fujii-Kuriyama, Y., Kato, S. Nature (2007)
