Gene Review:
UBP6 - Ubp6p
Saccharomyces cerevisiae S288c
Synonyms:
Deubiquitinating enzyme 6, Ubiquitin carboxyl-terminal hydrolase 6, Ubiquitin thioesterase 6, Ubiquitin-specific-processing protease 6, YFR010W
- Purification and characterization of UBP6, a new ubiquitin-specific protease in Saccharomyces cerevisiae. Park, K.C., Woo, S.K., Yoo, Y.J., Wyndham, A.M., Baker, R.T., Chung, C.H. Arch. Biochem. Biophys. (1997)
- Multiple associated proteins regulate proteasome structure and function. Leggett, D.S., Hanna, J., Borodovsky, A., Crosas, B., Schmidt, M., Baker, R.T., Walz, T., Ploegh, H., Finley, D. Mol. Cell (2002)
- Rad23 and Rpn10 serve as alternative ubiquitin receptors for the proteasome. Elsasser, S., Chandler-Militello, D., Müller, B., Hanna, J., Finley, D. J. Biol. Chem. (2004)
- Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome. Guterman, A., Glickman, M.H. J. Biol. Chem. (2004)
- Pleiotropic effects of Ubp6 loss on drug sensitivities and yeast prion are due to depletion of the free ubiquitin pool. Chernova, T.A., Allen, K.D., Wesoloski, L.M., Shanks, J.R., Chernoff, Y.O., Wilkinson, K.D. J. Biol. Chem. (2003)
- The Ubp6 family of deubiquitinating enzymes contains a ubiquitin-like domain: SUb. Wyndham, A.M., Baker, R.T., Chelvanayagam, G. Protein Sci. (1999)
- Ubiquitin depletion as a key mediator of toxicity by translational inhibitors. Hanna, J., Leggett, D.S., Finley, D. Mol. Cell. Biol. (2003)
- PDR2 Gain-of-function mutations eliminate the need for Pdr1 and require the UBP6 product for resistance to translational inhibitors. Keeven, J., Ko, D., Shallom, J., Uccelini, B., Golin, J. Curr. Genet. (2002)