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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

NIPSNAP1  -  nipsnap homolog 1 (C. elegans)

Homo sapiens

Synonyms: NipSnap1, Protein NipSnap homolog 1
 
 
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Disease relevance of NIPSNAP1

 

High impact information on NIPSNAP1

  • The NIPSNAP1 gene spans 26 kb of genomic sequence and shows to large introns in the 5'-region [2].
  • The NIPSNAP1 mRNA is 2.1 kb, is expressed ubiquitously at variable levels, with the highest expression in liver, is terminated by an uncommon ATTAAA polyadenylation site, and is capable of encoding a 284-amino-acid protein [2].
  • Although the function of the NIPSNAP protein family is unknown, clues about its role may reside in the co-expression of the C. elegans orthologue, within an operon encoding protein motifs known to be involved in vesicular transport [2].

References

  1. Identification of activity-regulated proteins in the postsynaptic density fraction. Satoh, K., Takeuchi, M., Oda, Y., Deguchi-Tawarada, M., Sakamoto, Y., Matsubara, K., Nagasu, T., Takai, Y. Genes Cells (2002) [Pubmed]
  2. Characterization of the human NIPSNAP1 gene from 22q12: a member of a novel gene family. Seroussi, E., Pan, H.Q., Kedra, D., Roe, B.A., Dumanski, J.P. Gene (1998) [Pubmed]
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