Gene Review:
CCC1 - Ccc1p
Saccharomyces cerevisiae S288c
Synonyms:
Cross-complementer of CSG1 protein 1, L8083.6, Protein CCC1, YLR220W
- CCC1 suppresses mitochondrial damage in the yeast model of Friedreich's ataxia by limiting mitochondrial iron accumulation. Chen, O.S., Kaplan, J. J. Biol. Chem. (2000)
- The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Pozos, T.C., Sekler, I., Cyert, M.S. Mol. Cell. Biol. (1996)
- A mitochondrial-vacuolar signaling pathway in yeast that affects iron and copper metabolism. Li, L., Kaplan, J. J. Biol. Chem. (2004)
- CCC1 is a transporter that mediates vacuolar iron storage in yeast. Li, L., Chen, O.S., McVey Ward, D., Kaplan, J. J. Biol. Chem. (2001)
- The role of the Saccharomyces cerevisiae CCC1 gene in the homeostasis of manganese ions. Lapinskas, P.J., Lin, S.J., Culotta, V.C. Mol. Microbiol. (1996)
- Sequence, mapping and disruption of CCC1, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants. Fu, D., Beeler, T., Dunn, T. Yeast (1994)