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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PPH21  -  phosphoprotein phosphatase 2A catalytic...

Saccharomyces cerevisiae S288c

Synonyms: D2180, Serine/threonine-protein phosphatase PP2A-1 catalytic subunit, YDL134C
 
 
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High impact information on PPH21

  • Two genes (PPH21 and PPH22) encoding the yeast homologues of protein serine-threonine phosphatase 2A have been cloned from a Saccharomyces cerevisiae genomic library using a rabbit protein phosphatase 2A cDNA as a hybridization probe [1].
 

Biological context of PPH21

 

Other interactions of PPH21

  • Early studies identified two bona fide protein phosphatase 2A (PP2A)-encoding genes in Saccharomyces cerevisiae, designated PPH21 and PPH22 [3].

References

  1. Saccharomyces cerevisiae protein phosphatase 2A performs an essential cellular function and is encoded by two genes. Sneddon, A.A., Cohen, P.T., Stark, M.J. EMBO J. (1990) [Pubmed]
  2. Overexpression of yeast PAM1 gene permits survival without protein phosphatase 2A and induces a filamentous phenotype. Hu, G.Z., Ronne, H. J. Biol. Chem. (1994) [Pubmed]
  3. Protein phosphatase 2A on track for nutrient-induced signalling in yeast. Zabrocki, P., Van Hoof, C., Goris, J., Thevelein, J.M., Winderickx, J., Wera, S. Mol. Microbiol. (2002) [Pubmed]
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