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Gene Review: 

YIP5  -  Yip5p

Saccharomyces cerevisiae S288c

Synonyms: G1832, Protein YIP5, YGL161C, YPT-interacting protein 5
 
 
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High impact information on YIP5

  • Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors [1].
  • The E. histolytica ARS consensus sequences allowed a yeast-integrating plasmid, YIP5, to replicate autonomously in S. cerevisiae [2].
  • The family includes yeast Yip1p, Yip4p, Yip5p, and Yif1p, and also their plant, insects, nematode, and mammalian homologues, suggesting their conserved function in a broad range of species [3].
  • Total DNA of the archaebacterium Methanococcus vannielii was digested with BamHI or BamHI/HindIII, cloned with plasmid Yip5 and analyzed for sequences capable of autonomous replication (ARSs) in the eukaryote Saccharomyces cerevisiae [4].
  • The original 4.2-kb mitochondrial DNA fragment, as well as the minimal 917-bp subfragment in vector pFL1-E (a variant of YIP5, lacking an origin of replication in yeast), were then tested for their ability to replicate autonomously in another fungus, Kluyveromyces lactis [5].

References

  1. Identification of the novel proteins Yip4p and Yip5p as Rab GTPase interacting factors. Calero, M., Winand, N.J., Collins, R.N. FEBS Lett. (2002) [Pubmed]
  2. Characterisation of a repetitive DNA family from Entamoeba histolytica containing Saccharomyces cerevisiae ARS consensus sequences. Lohia, A., Haider, N., Biswas, B.B. Gene (1990) [Pubmed]
  3. Identification of a five-pass transmembrane protein family localizing in the Golgi apparatus and the ER. Shakoori, A., Fujii, G., Yoshimura, S., Kitamura, M., Nakayama, K., Ito, T., Ohno, H., Nakamura, N. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
  4. Cloning of DNA sequences from Methanococcus vannielii capable of autonomous replication in yeast. Meile, L., Leisinger, T., Reeve, J.N. Arch. Microbiol. (1985) [Pubmed]
  5. Sequence analysis of a Papaver somniferum L. mitochondrial DNA fragment promoting autonomous plasmid replication in Saccharomyces cerevisiae and Kluyveromyces lactis. Farkasovská, J. Curr. Genet. (1993) [Pubmed]
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