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Gene Review

CBC2  -  Cbc2p

Saccharomyces cerevisiae S288c

Synonyms: 20 kDa nuclear cap-binding protein, CBP20, MUD13, NCBP 20 kDa subunit, Nuclear cap-binding protein subunit 2, ...
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High impact information on CBC2

  • In contrast we find that nuclear cap binding proteins (CBP-20 and 80), eIF4G, and PAB-1 are absolutely required for development [1].
  • Deletion of CBP80 or CBP20 in combination with certain temperature-sensitive npl3 mutant alleles fail to grow and thus display a synthetic lethal relationship [2].
  • In this report, we define a genetic relationship between NPL3 and the nonessential genes encoding the subunits of the cap-binding complex (CBP80 and CBP20) [2].
  • Two new meiosis-specific genes, SAE1 and SAE3, have been identified in a screen for mutations that confer an intermediate block in meiotic prophase [3].

Biological context of CBC2


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