Gene Review:
PRP22 - DEAH-box ATP-dependent RNA helicase PRP22
Saccharomyces cerevisiae S288c
Synonyms:
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22, YER013W
Puoti,
Kimble,
McPheeters,
Schwer,
Muhlenkamp,
McPheeters,
Muhlenkamp,
Schwer,
Meszaros,
Schwer,
Gross,
- Requirement of the RNA helicase-like protein PRP22 for release of messenger RNA from spliceosomes. Company, M., Arenas, J., Abelson, J. Nature (1991)
- RNA helicase dynamics in pre-mRNA splicing. Schwer, B., Meszaros, T. EMBO J. (2000)
- Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing. Schwer, B., Gross, C.H. EMBO J. (1998)
- Identification of a putative RNA helicase (HRH1), a human homolog of yeast Prp22. Ono, Y., Ohno, M., Shimura, Y. Mol. Cell. Biol. (1994)
- Cloning and characterization of a putative human RNA helicase gene of the DEAH-box protein family. Imamura, O., Sugawara, M., Furuichi, Y. Biochem. Biophys. Res. Commun. (1997)
- Interaction of the yeast DExH-box RNA helicase prp22p with the 3' splice site during the second step of nuclear pre-mRNA splicing. McPheeters, D.S., Schwer, B., Muhlenkamp, P. Nucleic Acids Res. (2000)
- Characterization of dominant-negative mutants of the DEAH-box splicing factors Prp22 and Prp16. Schneider, S., Hotz, H.R., Schwer, B. J. Biol. Chem. (2002)
- The hermaphrodite sperm/oocyte switch requires the Caenorhabditis elegans homologs of PRP2 and PRP22. Puoti, A., Kimble, J. Proc. Natl. Acad. Sci. U.S.A. (2000)
- Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast. McPheeters, D.S., Muhlenkamp, P. Mol. Cell. Biol. (2003)
- A human RNA helicase-like protein, HRH1, facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. Ohno, M., Shimura, Y. Genes Dev. (1996)
- A conserved epitope on a subset of SR proteins defines a larger family of Pre-mRNA splicing factors. Neugebauer, K.M., Stolk, J.A., Roth, M.B. J. Cell Biol. (1995)
- Motifs IV and V in the DEAH box splicing factor Prp22 are important for RNA unwinding, and helicase-defective Prp22 mutants are suppressed by Prp8. Schneider, S., Campodonico, E., Schwer, B. J. Biol. Chem. (2004)
- The first ATPase domain of the yeast 246-kDa protein is required for in vivo unwinding of the U4/U6 duplex. Kim, D.H., Rossi, J.J. RNA (1999)
- Mapping the putative RNA helicase genes by sequence overlapping. Chang, T.H., Baum, B. Yeast (1992)
- The mammalian homologue of Prp16p is overexpressed in a cell line tolerant to Leflunomide, a new immunoregulatory drug effective against rheumatoid arthritis. Ortlepp, D., Laggerbauer, B., Müllner, S., Achsel, T., Kirschbaum, B., Lührmann, R. RNA (1998)