Gene Review:
SRB4 - Srb4p
Saccharomyces cerevisiae S288c
Synonyms:
MED17, Mediator complex subunit 17, Mediator of RNA polymerase II transcription subunit 17, Suppressor of RNA polymerase B 4, YER022W
- Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo. Lee, D., Lis, J.T. Nature (1998)
- Different upstream transcriptional activators have distinct coactivator requirements. Lee, D.K., Kim, S., Lis, J.T. Genes Dev. (1999)
- Activated transcription independent of the RNA polymerase II holoenzyme in budding yeast. McNeil, J.B., Agah, H., Bentley, D. Genes Dev. (1998)
- An activator target in the RNA polymerase II holoenzyme. Koh, S.S., Ansari, A.Z., Ptashne, M., Young, R.A. Mol. Cell (1998)
- Requirement for a functional interaction between mediator components Med6 and Srb4 in RNA polymerase II transcription. Lee, Y.C., Kim, Y.J. Mol. Cell. Biol. (1998)
- Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation. Han, S.J., Lee, Y.C., Gim, B.S., Ryu, G.H., Park, S.J., Lane, W.S., Kim, Y.J. Mol. Cell. Biol. (1999)
- Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme. Lee, T.I., Wyrick, J.J., Koh, S.S., Jennings, E.G., Gadbois, E.L., Young, R.A. Mol. Cell. Biol. (1998)
- The structural and functional organization of the yeast mediator complex. Kang, J.S., Kim, S.H., Hwang, M.S., Han, S.J., Lee, Y.C., Kim, Y.J. J. Biol. Chem. (2001)
- The classical srb4-138 mutant allele causes dissociation of yeast Mediator. Linder, T., Zhu, X., Baraznenok, V., Gustafsson, C.M. Biochem. Biophys. Res. Commun. (2006)