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Gene Review

flhA  -  flagellar biosynthesis protein FlhA

Pseudomonas aeruginosa PAO1

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High impact information on flhA


Biological context of flhA

  • Deletion of the flhA promoter upstream of the RNA polymerase binding site did not result in a significant loss of promoter activity [2].
  • Infection of cells with an internalization-defective flhA mutant of P. aeruginosa was associated with less ERK 1/2 tyrosine phosphorylation than infection with wild-type invasive P. aeruginosa [3].

Analytical, diagnostic and therapeutic context of flhA

  • However, loss of motility was not sufficient to explain the reduced invasion by flhA mutants, since centrifugation of bacteria onto cells did not restore invasion to wild-type levels [1].


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