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Gene Review

Picalm  -  phosphatidylinositol binding clathrin...

Rattus norvegicus

Synonyms: Calm, Clathrin assembly lymphoid myeloid leukemia protein, Phosphatidylinositol-binding clathrin assembly protein, rCALM
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High impact information on Picalm


Biological context of Picalm


Analytical, diagnostic and therapeutic context of Picalm

  • Molecular cloning of clathrin assembly protein gene (rCALM) and its differential expression to AP180 in rat brain [3].
  • The mRNA expression of rCALM and AP180 by in situ hybridization histochemistry revealed that the rCALM mRNA was more intensely expressed than that of AP180, and the distribution patterns were different from each other [3].


  1. Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes. Ford, M.G., Pearse, B.M., Higgins, M.K., Vallis, Y., Owen, D.J., Gibson, A., Hopkins, C.R., Evans, P.R., McMahon, H.T. Science (2001) [Pubmed]
  2. Synaptic distribution of the endocytic accessory proteins AP180 and CALM. Yao, P.J., Petralia, R.S., Bushlin, I., Wang, Y., Furukawa, K. J. Comp. Neurol. (2005) [Pubmed]
  3. Molecular cloning of clathrin assembly protein gene (rCALM) and its differential expression to AP180 in rat brain. Kim, H.L., Lee, S.C. Exp. Mol. Med. (1999) [Pubmed]
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