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Gene Review

metI  -  DL-methionine transporter subunit

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK0198, JW0194, metD, yaeE
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Disease relevance of metI

  • The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ) [1].

High impact information on metI


Biological context of metI

  • An S-box sequence, which is located upstream of the metI gene, is involved in the regulation of the metIC operon [6].
  • Both activities respond identically to gene dosage of metD and are both restored in revertants or transductants [5].


  1. The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ). Merlin, C., Gardiner, G., Durand, S., Masters, M. J. Bacteriol. (2002) [Pubmed]
  2. The metD D-methionine transporter locus of Escherichia coli is an ABC transporter gene cluster. Gál, J., Szvetnik, A., Schnell, R., Kálmán, M. J. Bacteriol. (2002) [Pubmed]
  3. Thermosensitive omsA mutation of Escherichia coli that causes thermoregulated release of periplasmic proteins. Tsuruoka, T., Ito, M., Tomioka, S., Hirata, A., Matsuhashi, M. J. Bacteriol. (1988) [Pubmed]
  4. Chromosomal locations of the genes for rRNA in Escherichia coli K-12. Ellwood, M., Nomura, M. J. Bacteriol. (1982) [Pubmed]
  5. Transport and utilization of D-methionine and other methionine sources in Escherichia coli. Kadner, R.J. J. Bacteriol. (1977) [Pubmed]
  6. The metIC operon involved in methionine biosynthesis in Bacillus subtilis is controlled by transcription antitermination. Auger, S., Yuen, W.H., Danchin, A., Martin-Verstraete, I. Microbiology (Reading, Engl.) (2002) [Pubmed]
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