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Gene Review

metI  -  DL-methionine transporter subunit

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK0198, JW0194, metD, yaeE
 
 
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Disease relevance of metI

  • The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ) [1].
 

High impact information on metI

 

Biological context of metI

  • An S-box sequence, which is located upstream of the metI gene, is involved in the regulation of the metIC operon [6].
  • Both activities respond identically to gene dosage of metD and are both restored in revertants or transductants [5].

References

  1. The Escherichia coli metD locus encodes an ABC transporter which includes Abc (MetN), YaeE (MetI), and YaeC (MetQ). Merlin, C., Gardiner, G., Durand, S., Masters, M. J. Bacteriol. (2002) [Pubmed]
  2. The metD D-methionine transporter locus of Escherichia coli is an ABC transporter gene cluster. Gál, J., Szvetnik, A., Schnell, R., Kálmán, M. J. Bacteriol. (2002) [Pubmed]
  3. Thermosensitive omsA mutation of Escherichia coli that causes thermoregulated release of periplasmic proteins. Tsuruoka, T., Ito, M., Tomioka, S., Hirata, A., Matsuhashi, M. J. Bacteriol. (1988) [Pubmed]
  4. Chromosomal locations of the genes for rRNA in Escherichia coli K-12. Ellwood, M., Nomura, M. J. Bacteriol. (1982) [Pubmed]
  5. Transport and utilization of D-methionine and other methionine sources in Escherichia coli. Kadner, R.J. J. Bacteriol. (1977) [Pubmed]
  6. The metIC operon involved in methionine biosynthesis in Bacillus subtilis is controlled by transcription antitermination. Auger, S., Yuen, W.H., Danchin, A., Martin-Verstraete, I. Microbiology (Reading, Engl.) (2002) [Pubmed]
 
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