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Gene Review

entD  -  phosphopantetheinyltransferase component...

Escherichia coli str. K-12 substr. MG1655

Synonyms: ECK0575, JW5085
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Disease relevance of entD

  • Three PPTases have been previously been identified in Escherichia coli K-12 and other E. coli strains by homology searches and are encoded by the genes acpS, entD and acpT [1].
  • Homologs of the E. coli entD and Vibrio cholerae vibH genes were also detected in the flanking regions immediately adjacent to the B. abortus dhbCEBA operon, suggesting that B. abortus has the genetic capacity to produce a more complex 2,3-DHBA-based siderophore [2].

High impact information on entD


Chemical compound and disease context of entD

  • The Escherichia coli entD gene encodes a product necessary for the synthesis of the iron-chelating and transport molecule enterobactin (Ent); cells harbouring entD mutations fail to grow in iron-deficient environments [4].

Biological context of entD


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