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Gene Review

groEL  -  molecular chaperone GroEL

Synechocystis sp. PCC 6803

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Disease relevance of groEL

  • Using a groEL gene of Synechococcus sp. PCC 7942 as a DNA probe, a 4.8-kilobase pair (kbp) BamHI fragment of chromosomal DNA of Synechocystis sp. PCC 6803 was cloned [1].

High impact information on groEL


Anatomical context of groEL

  • The coexistence of divergent groEL/cpn60 genes in different genomes in one cell offers insights into gene transfer from evolving chloroplasts to cell nuclei and convergent gene evolution in chlorophyll a/b versus chlorophyll a/c/phycobilin eukaryotic lineages [2].


  1. A second groEL-like gene, organized in a groESL operon is present in the genome of Synechocystis sp. PCC 6803. Lehel, C., Los, D., Wada, H., Györgyei, J., Horváth, I., Kovács, E., Murata, N., Vigh, L. J. Biol. Chem. (1993) [Pubmed]
  2. Ancient gene duplication and differential gene flow in plastid lineages: the GroEL/Cpn60 example. Wastl, J., Fraunholz, M., Zauner, S., Douglas, S., Maier, U.G. J. Mol. Evol. (1999) [Pubmed]
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