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Gene Review

rfaF  -  ADP-heptose--LPS heptosyltransferase

Escherichia coli O157:H7 str. EDL933

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Disease relevance of rfaF

  • Complementation of a panel of Salmonella typhimurium mutants with defined defects in rfa loci demonstrated conclusively that the Isi-1 gene of MS11 is functionally homologous to the rfaF gene, which encodes heptosyltransferase II in both E. coli and S. typhimurium [1].
  • Deletion of the heptosyltransferase genes rfaC and rfaF in Escherichia coli K-12 results in an Re-type lipopolysaccharide with a high degree of 2-aminoethanol phosphate substitution [2].

High impact information on rfaF


Chemical compound and disease context of rfaF


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