Gene Review:
FAM65B - family with sequence similarity 65, member B
Homo sapiens
Synonyms:
C6orf32, DIFF40, DIFF48, KIAA0386, MYONAP, ...
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High impact information on C6orf32
- It is not present in a wide variety of proliferating cancer cells, but PL48 mRNA shows marked expression during cytotrophoblast and granulocyte lineage-specific HL-60 promyelocytic cell differentiation induced by DMSO [1].
- PL48: a novel gene associated with cytotrophoblast and lineage-specific HL-60 cell differentiation [1].
- PL48 contains an open reading frame coding for a 537-amino acid protein, has multiple potential PKC, casein kinase II, and cAMP/cGMP-dependent kinase phosphorylation sites, and N-linked glycosylation sites [1].
Anatomical context of C6orf32
- The cDNA for a novel gene, PL48, isolated by subtractive hybridization between undifferentiated human term cytotrophoblast and differentiating cytotrophoblast, has been cloned and sequenced [1].
References
- PL48: a novel gene associated with cytotrophoblast and lineage-specific HL-60 cell differentiation. Dakour, J., Li, H., Morrish, D.W. Gene (1997) [Pubmed]
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