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MeSH Review:

Nail Biting

Leonard, H.L. et al., Bayo, J. et al., Wells, J.H. et al., Narang, R.L. et al., Wadden, P. et al.

Bayo, Moreno-Grau, Martinez, Moreno, Angosto, Guillén Pérez, Garcia Marcos, Moreno-Clavel,

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Psychiatry related information on Nail Biting

Twenty-five adult subjects with severe morbid onychophagia (nail biting) and no history of obsessive-compulsive disorder were enrolled in a 10-week double-blind cross-over trial of clomipramine hydrochloride and desipramine hydrochloride [1].

High impact information on Nail Biting

For the 14 subjects who completed the study, clomipramine hydrochloride (mean +/- SD dose, 120 +/- 48 mg/d) was superior to desipramine hydrochloride (mean +/- SD dose, 135 +/- 53 mg/d) in decreasing nail biting as measured by a repeated-measures analysis of variance on the Nail Biting Severity, Nailbiting Impairment, and Clinical Progress scales [1].
When a multifactor ANOVA was carried out, the associations between home antiquity, nail biting habit, and jaw with tooth lead levels, as well as those between zone of residence and tooth cadmium levels were found to persist [2].
CONCLUSION: Severe onychophagia appears to manage the level of tension experienced by an individual, instead of dramatically reducing it in times of crisis [3].
Cessation of nail-biting and bupropion [4].
In the HSE group, symptoms like nail biting, food refusal, food fads and temper tantrums were significantly more [5].

References

A double-blind comparison of clomipramine and desipramine treatment of severe onychophagia (nail biting). Leonard, H.L., Lenane, M.C., Swedo, S.E., Rettew, D.C., Rapoport, J.L. Arch. Gen. Psychiatry (1991) [Pubmed]
Environmental and physiological factors affecting lead and cadmium levels in deciduous teeth. Bayo, J., Moreno-Grau, S., Martinez, M.J., Moreno, J., Angosto, J.M., Guillén Pérez, J., Garcia Marcos, L., Moreno-Clavel, J. Arch. Environ. Contam. Toxicol. (2001) [Pubmed]
The self-mutilative nature of severe onychophagia: a comparison with self-cutting. Wells, J.H., Haines, J., Williams, C.L., Brain, K.L. Canadian journal of psychiatry. Revue canadienne de psychiatrie. (1999) [Pubmed]
Cessation of nail-biting and bupropion. Wadden, P., Pawliuk, G. Canadian journal of psychiatry. Revue canadienne de psychiatrie. (1999) [Pubmed]
Spectrum of psychiatric symptomatology in children in high and low socio-economic groups in Ludhiana. Narang, R.L., Jain, B.K., Gupta, M.S., Gupta, R. Indian pediatrics. (1991) [Pubmed]

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