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MeSH Review:

Coronavirus, Canine

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Disease relevance of Coronavirus, Canine

The crystal structure of Clostridium botulinum neurotoxin B appeared to be structurally adaptable to human and canine coronavirus spike protein sequences and it was successfully used to model the two subunits of SARS coronavirus spike glycoprotein [1].

High impact information on Coronavirus, Canine

We have cloned, sequenced and expressed the spike (S) gene of canine coronavirus (CCV; strain K378) [2].
No cross-reaction was found between the N195 protein and antibodies against chicken, pig, and canine coronaviruses [3].
Feline and canine coronaviruses are released from the basolateral side of polarized epithelial LLC-PK1 cells expressing the recombinant feline aminopeptidase-N cDNA [4].
Cloning, sequencing and expression of the S protein gene from two geographically distinct strains of canine coronavirus [5].
Four hundred twenty-five sera were tested for evidence of exposure to canine coronavirus by means of an indirect fluorescent antibody procedure [6].

References

Molecular modelling of S1 and S2 subunits of SARS coronavirus spike glycoprotein. Spiga, O., Bernini, A., Ciutti, A., Chiellini, S., Menciassi, N., Finetti, F., Causarono, V., Anselmi, F., Prischi, F., Niccolai, N. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
Nucleotide sequence and expression of the spike (S) gene of canine coronavirus and comparison with the S proteins of feline and porcine coronaviruses. Wesseling, J.G., Vennema, H., Godeke, G.J., Horzinek, M.C., Rottier, P.J. J. Gen. Virol. (1994) [Pubmed]
Development of a Western blot assay for detection of antibodies against coronavirus causing severe acute respiratory syndrome. He, Q., Chong, K.H., Chng, H.H., Leung, B., Ling, A.E., Wei, T., Chan, S.W., Ooi, E.E., Kwang, J. Clin. Diagn. Lab. Immunol. (2004) [Pubmed]
Feline and canine coronaviruses are released from the basolateral side of polarized epithelial LLC-PK1 cells expressing the recombinant feline aminopeptidase-N cDNA. Rossen, J.W., Kouame, J., Goedheer, A.J., Vennema, H., Rottier, P.J. Arch. Virol. (2001) [Pubmed]
Cloning, sequencing and expression of the S protein gene from two geographically distinct strains of canine coronavirus. Horsburgh, B.C., Brown, T.D. Virus Res. (1995) [Pubmed]
Serologic survey for canine coronavirus in wolves from Alaska. Zarnke, R.L., Evermann, J., Ver Hoef, J.M., McNay, M.E., Boertje, R.D., Gardner, C.L., Adams, L.G., Dale, B.W., Burch, J. J. Wildl. Dis. (2001) [Pubmed]

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