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MeSH Review

LLC-PK1 Cells

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Disease relevance of LLC-PK1 Cells


High impact information on LLC-PK1 Cells


Chemical compound and disease context of LLC-PK1 Cells


Biological context of LLC-PK1 Cells


Anatomical context of LLC-PK1 Cells


Associations of LLC-PK1 Cells with chemical compounds


Gene context of LLC-PK1 Cells


Analytical, diagnostic and therapeutic context of LLC-PK1 Cells


  1. Multiple instability-regulating sites in the 3' untranslated region of the urokinase-type plasminogen activator mRNA. Nanbu, R., Menoud, P.A., Nagamine, Y. Mol. Cell. Biol. (1994) [Pubmed]
  2. The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells. Stevens, J., Hayden, P., Taylor, G. J. Biol. Chem. (1986) [Pubmed]
  3. Captopril reverses high-glucose-induced growth effects on LLC-PK1 cells partly by decreasing transforming growth factor-beta receptor protein expressions. Guh, J.Y., Yang, M.L., Yang, Y.L., Chang, C.C., Chuang, L.Y. J. Am. Soc. Nephrol. (1996) [Pubmed]
  4. Prostaglandin F2 alpha inhibits the ammoniagenic response to acute acidosis in LLC-PK1 cells. Sahai, A., Goyal, M., Tannen, R.L. J. Am. Soc. Nephrol. (1990) [Pubmed]
  5. Endonuclease induced DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. Hagar, H., Ueda, N., Shah, S.V. Kidney Int. (1996) [Pubmed]
  6. Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells. Bouley, R., Breton, S., Sun, T., McLaughlin, M., Nsumu, N.N., Lin, H.Y., Ausiello, D.A., Brown, D. J. Clin. Invest. (2000) [Pubmed]
  7. Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells. Evers, R., Zaman, G.J., van Deemter, L., Jansen, H., Calafat, J., Oomen, L.C., Oude Elferink, R.P., Borst, P., Schinkel, A.H. J. Clin. Invest. (1996) [Pubmed]
  8. Studies of renal injury. II. Activation of the glucose transporter 1 (GLUT1) gene and glycolysis in LLC-PK1 cells under Ca2+ stress. Dominguez, J.H., Song, B., Liu-Chen, S., Qulali, M., Howard, R., Lee, C.H., McAteer, J. J. Clin. Invest. (1996) [Pubmed]
  9. Clusterin promotes the aggregation and adhesion of renal porcine epithelial cells. Silkensen, J.R., Skubitz, K.M., Skubitz, A.P., Chmielewski, D.H., Manivel, J.C., Dvergsten, J.A., Rosenberg, M.E. J. Clin. Invest. (1995) [Pubmed]
  10. Oxalate toxicity in LLC-PK1 cells: role of free radicals. Scheid, C., Koul, H., Hill, W.A., Luber-Narod, J., Kennington, L., Honeyman, T., Jonassen, J., Menon, M. Kidney Int. (1996) [Pubmed]
  11. Tyrosine phosphorylation in DNA damage and cell death in hypoxic injury to LLC-PK1 cells. Hagar, H., Ueda, N., Shah, S.V. Kidney Int. (1997) [Pubmed]
  12. Role of enhanced ceramide generation in DNA damage and cell death in chemical hypoxic injury to LLC-PK1 cells. Ueda, N., Kaushal, G.P., Hong, X., Shah, S.V. Kidney Int. (1998) [Pubmed]
  13. Angiotensin II-stimulated hypertrophy of LLC-PK1 cells depends on the induction of the cyclin-dependent kinase inhibitor p27Kip1. Wolf, G., Stahl, R.A. Kidney Int. (1996) [Pubmed]
  14. Okadaic acid induction of the urokinase-type plasminogen activator gene occurs independently of cAMP-dependent protein kinase and protein kinase C and is sensitive to protein synthesis inhibition. Nagamine, Y., Ziegler, A. EMBO J. (1991) [Pubmed]
  15. Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a metallothionein-alpha i-2 fusion gene in LLC-PK1 cells. Ercolani, L., Stow, J.L., Boyle, J.F., Holtzman, E.J., Lin, H., Grove, J.R., Ausiello, D.A. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  16. Osmotic diuretics induce adenosine A1 receptor expression and protect renal proximal tubular epithelial cells against cisplatin-mediated apoptosis. Pingle, S.C., Mishra, S., Marcuzzi, A., Bhat, S.G., Sekino, Y., Rybak, L.P., Ramkumar, V. J. Biol. Chem. (2004) [Pubmed]
  17. ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3). Hirohashi, T., Suzuki, H., Takikawa, H., Sugiyama, Y. J. Biol. Chem. (2000) [Pubmed]
  18. Ouabain assembles signaling cascades through the caveolar Na+/K+-ATPase. Wang, H., Haas, M., Liang, M., Cai, T., Tian, J., Li, S., Xie, Z. J. Biol. Chem. (2004) [Pubmed]
  19. A heterotrimeric G protein, G alpha i-3, on Golgi membranes regulates the secretion of a heparan sulfate proteoglycan in LLC-PK1 epithelial cells. Stow, J.L., de Almeida, J.B., Narula, N., Holtzman, E.J., Ercolani, L., Ausiello, D.A. J. Cell Biol. (1991) [Pubmed]
  20. Avian and mammalian receptors for 1,25-dihydroxyvitamin D3: in vitro translation to characterize size and hormone-dependent regulation. Mangelsdorf, D.J., Pike, J.W., Haussler, M.R. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
  21. High affinity phlorizin binding to the LLC-PK1 cells exhibits a sodium:phlorizin stoichiometry of 2:1. Moran, A., Davis, L.J., Turner, R.J. J. Biol. Chem. (1988) [Pubmed]
  22. Heterogeneity of protein kinase C-mediated rapid regulation of Na/K-ATPase in kidney epithelial cells. Middleton, J.P., Khan, W.A., Collinsworth, G., Hannun, Y.A., Medford, R.M. J. Biol. Chem. (1993) [Pubmed]
  23. Increase in membrane fluidity and opening of tight junctions have similar effects on sodium-coupled uptakes in renal epithelial cells. Friedlander, G., Shahedi, M., Le Grimellec, C., Amiel, C. J. Biol. Chem. (1988) [Pubmed]
  24. All-trans-retinoic acid stimulates synthesis of cyclic ADP-ribose in renal LLC-PK1 cells. Beers, K.W., Chini, E.N., Dousa, T.P. J. Clin. Invest. (1995) [Pubmed]
  25. Hydrogen peroxide-induced renal injury. A protective role for pyruvate in vitro and in vivo. Salahudeen, A.K., Clark, E.C., Nath, K.A. J. Clin. Invest. (1991) [Pubmed]
  26. Internalization of vasopressin analogs in kidney and smooth muscle cells: evidence for receptor-mediated endocytosis in cells with V2 or V1 receptors. Lutz, W., Sanders, M., Salisbury, J., Kumar, R. Proc. Natl. Acad. Sci. U.S.A. (1990) [Pubmed]
  27. Sodium butyrate increases glucose transporter expression in LLC-PK1 cells. Takano, M., Rhoads, D.B., Isselbacher, K.J. Proc. Natl. Acad. Sci. U.S.A. (1988) [Pubmed]
  28. Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3). Hirohashi, T., Suzuki, H., Sugiyama, Y. J. Biol. Chem. (1999) [Pubmed]
  29. Interaction of lp-dlg/KIAA0583, a membrane-associated guanylate kinase family protein, with vinexin and beta-catenin at sites of cell-cell contact. Wakabayashi, M., Ito, T., Mitsushima, M., Aizawa, S., Ueda, K., Amachi, T., Kioka, N. J. Biol. Chem. (2003) [Pubmed]
  30. The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane. Raggers, R.J., van Helvoort, A., Evers, R., van Meer, G. J. Cell. Sci. (1999) [Pubmed]
  31. Parathyroid hormone-related protein is an autocrine modulator of rabbit proximal tubule cell growth. García-Ocaña, A., De Miguel, F., Peñaranda, C., Albar, J.P., Sarasa, J.L., Esbrit, P. J. Bone Miner. Res. (1995) [Pubmed]
  32. Cloning of porcine 25-hydroxyvitamin D3 1alpha-hydroxylase and its regulation by cAMP in LLC-PK1 cells. Yoshida, T., Yoshida, N., Nakamura, A., Monkawa, T., Hayashi, M., Saruta, T. J. Am. Soc. Nephrol. (1999) [Pubmed]
  33. Phosphorylation of serine 256 is required for cAMP-dependent regulatory exocytosis of the aquaporin-2 water channel. Fushimi, K., Sasaki, S., Marumo, F. J. Biol. Chem. (1997) [Pubmed]
  34. Molecular cloning of NHE3 from LLC-PK1 cells and localization in pig kidney. Shugrue, C.A., Obermüller, N., Bachmann, S., Slayman, C.W., Reilly, R.F. J. Am. Soc. Nephrol. (1999) [Pubmed]
  35. Effects of cardiac glycosides on sodium pump expression and function in LLC-PK1 and MDCK cells. Liu, J., Periyasamy, S.M., Gunning, W., Fedorova, O.V., Bagrov, A.Y., Malhotra, D., Xie, Z., Shapiro, J.I. Kidney Int. (2002) [Pubmed]
  36. LLC-PK1 cells model 11 beta-hydroxysteroid dehydrogenase type 2 regulation of glucocorticoid access to renal mineralocorticoid receptors. Leckie, C., Chapman, K.E., Edwards, C.R., Seckl, J.R. Endocrinology (1995) [Pubmed]
  37. Immunolocalization of V1 vasopressin receptors in the rat kidney using anti-receptor antibodies. Gonzalez, C.B., Figueroa, C.D., Reyes, C.E., Caorsi, C.E., Troncoso, S., Menzel, D. Kidney Int. (1997) [Pubmed]
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