Disease relevance of Muscle Tonus

• CONCLUSION: Mild changes in truncal muscle tonus with prominent neck dystonia and rigidity are characteristic of progressive supranuclear palsy [1].

High impact information on Muscle Tonus

• Chronically administered 3-nitropropionic acid produces selective lesions in the striatum and reduces muscle tonus [2].
• At very high doses of haloperidol and later in the action of the drug, muscle tonus appears to be weakened, reducing the likelihood of jumping [3].
• Muscle tonus was also altered by systemic injections of mephenesin, a centrally acting muscle relaxant [4].
• Initially described as a peptidergic neuromuscular transmitter, it now appears that proctolin is a major arthropod neurohormone modulating nervous activity, muscle tonus and contractile force [5].
• The Bi-Digital O-Ring Test, originally developed by Dr. Omura, utilizes changes in the degree of strength of voluntary movements of muscles of the fingers under a definite muscle tonus, making Bi-Digital O-Rings, as an indicator of pathology in the body [6].

Associations of Muscle Tonus with chemical compounds

• 2. L-glutamate, at a concentration of 10(-4) to 10(-3) M, caused an increase in the frequency of contractions and in muscle tonus [7].
• Lorazepam induced in this trial a marked relief of anxiety after 60 minutes without changes in vital parameters nor in reflex activity or muscle tonus [8].
• Increasing the volume of epidural sufentanil, and similarly decreasing the concentration of the injection product, resulted in a potentiation of the analgesic properties of epidural sufentanil without affecting the effects of the drug on the pinna and cornea reflexes and on muscle tonus [9].

References