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High impact information on Usnea

  • Diffractaic acid and usnic acid were identified as the analgesic and antipyretic components of a lichen, Usnea diffracta [1].
  • Usnic acid and diffractaic acid as analgesic and antipyretic components of Usnea diffracta [1].
  • Parmelia caperata and Parmelia reticulata were positive in all, and in a descending order of positivity: Pseudovernia furfuracea, Evernia prunastri, Usnea spp, Ramalina lusitanica. d-Usnic and evernic acids and atranorin were the main responsible allergens [2].
  • Various solvent extracts of the lichen Usnea ghattensis showed good antioxidant activity [3].
  • Antiplatelet and antithrombotic activities of methanol extract of Usnea longissima [4].

Anatomical context of Usnea


Associations of Usnea with chemical compounds

  • Isolation of (+) usnic acid from Sudanese drug Usnea molliuscula [6].
  • In this study, the antiulcerogenic effect of a water extract obtained from the lichen species Usnea longissima was investigated using indomethacin-induced ulcer models in rats [7].
  • The usnic acid production by a mycobiont of the lichen Usnea hirta was higher in the liquid medium containing ammonium and nitrate ions than in those containing amino acids [8].

Gene context of Usnea

  • In Romania, Usnea barbata was mentioned in 1929 among the plants known by Romanian people with popular names: "Bear's beard", "Trees' dandruff", "Woman's long hair" (1). "Farmacia naturii" (2) and "Flora medicinală a Romaniei" (3) have mentioned that Usnea barbata (L) Mott contains usnic acid-substance with broad antibiotic spectrum [9].


  1. Usnic acid and diffractaic acid as analgesic and antipyretic components of Usnea diffracta. Okuyama, E., Umeyama, K., Yamazaki, M., Kinoshita, Y., Yamamoto, Y. Planta Med. (1995) [Pubmed]
  2. Contact sensitivity to lichens and compositae in Frullania dermatitis. Gonçalo, S. Contact Derm. (1987) [Pubmed]
  3. Antioxidant and antibacterial activities of lichen Usnea ghattensis in vitro. Behera, B.C., Verma, N., Sonone, A., Makhija, U. Biotechnol. Lett. (2005) [Pubmed]
  4. Antiplatelet and antithrombotic activities of methanol extract of Usnea longissima. Lee, K.A., Kim, M.S. Phytotherapy research : PTR. (2005) [Pubmed]
  5. Hepatotoxic effect of (+)usnic acid from Usnea siamensis Wainio in rats, isolated rat hepatocytes and isolated rat liver mitochondria. Pramyothin, P., Janthasoot, W., Pongnimitprasert, N., Phrukudom, S., Ruangrungsi, N. Journal of ethnopharmacology. (2004) [Pubmed]
  6. Isolation of (+) usnic acid from Sudanese drug Usnea molliuscula. Kheir, Y.M., Patel, M.B. Planta Med. (1975) [Pubmed]
  7. Effects of water extract of Usnea longissima on antioxidant enzyme activity and mucosal damage caused by indomethacin in rats. Halici, M., Odabasoglu, F., Suleyman, H., Cakir, A., Aslan, A., Bayir, Y. Phytomedicine (2005) [Pubmed]
  8. Influences of nitrogen sources on usnic acid production in a cultured Mycobiont of the lichen Usnea hirta (L.) Wigg. Kinoshita, Y., Yamamoto, Y., Kurokawa, T., Yoshimura, I. Biosci. Biotechnol. Biochem. (2001) [Pubmed]
  9. Contributions to the complex study of some lichens-Usnea genus. Pharmacological studies on Usnea barbata and Usnea hirta species. Dobrescu, D., Tănăsescu, M., Mezdrea, A., Ivan, C., Ordosch, E., Neagoe, F., Rizeanu, A., Trifu, L., Enescu, V. Romanian journal of physiology : physiological sciences / [Academia de Stiinte Medicale]. (1993) [Pubmed]
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