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MeSH Review

Prunella

 
 
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Disease relevance of Prunella

 

High impact information on Prunella

  • Large-scale screening of plant extracts indicated that rosmarinic acid (RosA) in extracts of Prunella vulgaris consistently inhibits the interaction between Lck SH2 and a peptide containing its consensus binding sequence (pYEEI) [2].
  • Competition for male reproductive investment elevates testosterone levels in female dunnocks, Prunella modularis [3].
  • Crude extracts of four Chinese herbs, Arctium lappa, Astragalus membranaceus, Andrographis paniculata, and Prunella vulgaris, were assessed in several tissue culture lines for anti-HIV activity and for cytotoxicity [4].
  • Isolation and characterization of an anti-HSV polysaccharide from Prunella vulgaris [5].
  • A water soluble substance was isolated from a Chinese herb, Prunella vulgaris, by hot water extraction, ethanol precipitation and gel permeation column chromatography [5].
 

Associations of Prunella with chemical compounds

References

  1. Leishmania infecting man and wild animals in Saudi Arabia. 6. Cutaneous leishmaniasis of man in the south-west. al-Zahrani, M.A., Peters, W., Evans, D.A., Smith, V., Ching Chin, I. Trans. R. Soc. Trop. Med. Hyg. (1989) [Pubmed]
  2. Rosmarinic acid inhibits TCR-induced T cell activation and proliferation in an Lck-dependent manner. Won, J., Hur, Y.G., Hur, E.M., Park, S.H., Kang, M.A., Choi, Y., Park, C., Lee, K.H., Yun, Y. Eur. J. Immunol. (2003) [Pubmed]
  3. Competition for male reproductive investment elevates testosterone levels in female dunnocks, Prunella modularis. Langmore, N.E., Cockrem, J.F., Candy, E.J. Proc. Biol. Sci. (2002) [Pubmed]
  4. Mechanism of inhibition of HIV-1 infection in vitro by purified extract of Prunella vulgaris. Yao, X.J., Wainberg, M.A., Parniak, M.A. Virology (1992) [Pubmed]
  5. Isolation and characterization of an anti-HSV polysaccharide from Prunella vulgaris. Xu, H.X., Lee, S.H., Lee, S.F., White, R.L., Blay, J. Antiviral Res. (1999) [Pubmed]
  6. Cytoprotectivity of Prunella vulgaris on doxorubicin-treated rat cardiomyocytes. Psotová, J., Chlopcíková, S., Miketová, P., Simánek, V. Fitoterapia (2005) [Pubmed]
 
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