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MeSH Review

Astragalus membranaceus

 
 
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Disease relevance of Astragalus membranaceus

 

High impact information on Astragalus membranaceus

  • Bioassay-guided fractionation resulted in the isolation of the isoflavones, formononetin, and calycosin from Astragalus membranaceus, and daidzein from Pueraria thomsonii as the PPAR-activating compounds [4].
  • (3R)-(-)-7,2'-Dihydroxy-3',4'-dimethyl isoflavan-7-O-beta-D-glucopyranoside and (6aR, 11aR) 9,10-di-methoxypterocarpan-3-O-beta-D-glucopyranoside were separated from the ethyl acetate extract of the root of Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao by high-speed counter-current chromatography (HSCCC) [5].
  • The immunopotentiating effect of the roots of Astragalus membranaceus, a medicinal herb, has been associated with its polysaccharide fractions (Astragalus polysaccharides, APS) [6].
  • Preparative isolation and purification of calycosin from Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao by high-speed counter-current chromatography [7].
  • An in vivo experiment was conducted to study the potential prebiotic effects of mushroom and herb polysaccharide extracts, Lentinus edodes extract (LenE), Tremella fuciformis extract, and Astragalus membranaceus Radix extract, on chicken growth and the cecal microbial ecosystem, as compared with the antibiotic Apramycin (APR) [8].
 

Biological context of Astragalus membranaceus

 

Associations of Astragalus membranaceus with chemical compounds

 

Gene context of Astragalus membranaceus

  • Messenger RNA expressions of vasopressin system and aquaporin-2 in adriamycin-induced nephrotic rats and effects of astragalus membranaceus [14].
  • We hypothesized that co-incubation of LAK cell precursors with a Chinese herbal extract (F3) of Astragalus membranaceus, (an immune modulator currently under study in our laboratory), along with a low concentration of rIL-2, would generate levels of LAK cell activity equivalent to those generated by high concentrations of rIL-2 alone [15].
  • Fractionated extract of Astragalus membranaceus, a Chinese medicinal herb, potentiates LAK cell cytotoxicity generated by a low dose of recombinant interleukin-2 [15].
 

Analytical, diagnostic and therapeutic context of Astragalus membranaceus

References

  1. Treatment of experimental Coxsackie B-3 viral myocarditis with Astragalus membranaceus in mice. Yang, Y.Z., Jin, P.Y., Guo, Q., Wu, W.Z., Pu, S.Y., Chen, H.Z., Yang, J.H., Wang, K.Q., Shi, J.Y., Gong, Z.X. Chin. Med. J. (1990) [Pubmed]
  2. The inhibitory effect of astragalus membranaceus on coxsackie B-3 virus RNA replication. Peng, T., Yang, Y., Riesemann, H., Kandolf, R. Chin. Med. Sci. J. (1995) [Pubmed]
  3. Effects of beta-glucan obtained from the Chinese herb Astragalus membranaceus and lipopolysaccharide challenge on performance, immunological, adrenal, and somatotropic responses of weanling pigs. Mao, X.F., Piao, X.S., Lai, C.H., Li, D.F., Xing, J.J., Shi, B.L. J. Anim. Sci. (2005) [Pubmed]
  4. Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARalpha, PPARgamma, and adipocyte differentiation in vitro. Shen, P., Liu, M.H., Ng, T.Y., Chan, Y.H., Yong, E.L. J. Nutr. (2006) [Pubmed]
  5. Preparative isolation and purification of isoflavan and pterocarpan glycosides from Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao by high-speed counter-current chromatography. Ma, X., Tu, P., Chen, Y., Zhang, T., Wei, Y., Ito, Y. Journal of chromatography. A. (2004) [Pubmed]
  6. A study on the immune receptors for polysaccharides from the roots of Astragalus membranaceus, a Chinese medicinal herb. Shao, B.M., Xu, W., Dai, H., Tu, P., Li, Z., Gao, X.M. Biochem. Biophys. Res. Commun. (2004) [Pubmed]
  7. Preparative isolation and purification of calycosin from Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao by high-speed counter-current chromatography. Ma, X., Zhang, T., Wei, Y., Tu, P., Chen, Y., Ito, Y. Journal of chromatography. A. (2002) [Pubmed]
  8. Effects of mushroom and herb polysaccharides, as alternatives for an antibiotic, on the cecal microbial ecosystem in broiler chickens. Guo, F.C., Williams, B.A., Kwakkel, R.P., Li, H.S., Li, X.P., Luo, J.Y., Li, W.K., Verstegen, M.W. Poult. Sci. (2004) [Pubmed]
  9. Macrophage activation by polysaccharide isolated from Astragalus membranaceus. Lee, K.Y., Jeon, Y.J. Int. Immunopharmacol. (2005) [Pubmed]
  10. Effects of compound injection of Pyrola rotundifolia L and Astragalus membranaceus Bge on experimental guinea pigs' gentamicin ototoxicity. Xuan, W., Dong, M., Dong, M. The Annals of otology, rhinology, and laryngology. (1995) [Pubmed]
  11. Flavonoids and phenol carboxylic acids in the oriental medicinal plant Astragalus membranaceus acclimated in Poland. Matkowski, A., Woźniak, D., Lamer-Zarawska, E., Oszmiański, J., Leszczyńska, A. Z. Naturforsch., C, J. Biosci. (2003) [Pubmed]
  12. Protective effects of Astragalus saponin I on early stage of diabetic nephropathy in rats. Yin, X., Zhang, Y., Wu, H., Zhu, X., Zheng, X., Jiang, S., Zhuo, H., Shen, J., Li, L., Qiu, J. J. Pharmacol. Sci. (2004) [Pubmed]
  13. Astragalus membranaceus reduces free radical-mediated injury to renal tubules in rabbits receiving high-energy shock waves. Sheng, B.W., Chen, X.F., Zhao, J., He, D.L., Nan, X.Y. Chin. Med. J. (2005) [Pubmed]
  14. Messenger RNA expressions of vasopressin system and aquaporin-2 in adriamycin-induced nephrotic rats and effects of astragalus membranaceus. Ma, J., Fan, S., Chen, J., Gu, Y., Lin, S. Chin. Med. J. (1999) [Pubmed]
  15. Fractionated extract of Astragalus membranaceus, a Chinese medicinal herb, potentiates LAK cell cytotoxicity generated by a low dose of recombinant interleukin-2. Chu, D.T., Lepe-Zuniga, J., Wong, W.L., LaPushin, R., Mavligit, G.M. Journal of clinical & laboratory immunology. (1988) [Pubmed]
  16. Astragaloside IV and polysaccharide production by hairy roots of Astragalus membranaceus in bioreactors. Du, M., Wu, X.J., Ding, J., Hu, Z.B., White, K.N., Branford-White, C.J. Biotechnol. Lett. (2003) [Pubmed]
  17. Hepatoprotective effects of astraglus root. Zhang, Z.L., Wen, Q.Z., Liu, C.X. Journal of ethnopharmacology. (1990) [Pubmed]
 
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