Disease relevance of Moyamoya Disease

• This raises the possibility of a link between protein C deficiency and Down syndrome with moyamoya syndrome [1].
• An adult case of moyamoya syndrome that developed dural sinus thrombosis associated with protein C deficiency: case report and literature review [2].

High impact information on Moyamoya Disease

• CONCLUSION: Factor V Leiden mutation may cause large cerebral vessel occlusion with moyamoya syndrome in adults [3].
• Surgery for moyamoya syndrome? Yes [4].
• RESULTS: Compared with the control group, children with moyamoya syndrome exhibited significantly elevated CSF levels of soluble vascular cell adhesion molecule Type 1, intercellular adhesion molecule Type 1, and E-selectin [5].
• Moyamoya syndrome in cocaine-dependent patients [6].
• Moyamoya disease (moyamoya syndrome) and coarctation of the aorta [7].

Chemical compound and disease context of Moyamoya Disease

• We have designed a new method of administering N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP) for experimental induction of moyamoya disease using an intravascular interventional technique combined with rod-shaped embolic materials made from lactic acid-glycolic acid copolymer [8].
• Increased concentrations of PF4 and beta TG were found in two patients with Moya-Moya disease [9].

Anatomical context of Moyamoya Disease

• Guidelines for the diagnosis and treatment of spontaneous occlusion of the circle of Willis ('moyamoya' disease). Research Committee on Spontaneous Occlusion of the Circle of Willis (Moyamoya Disease) of the Ministry of Health and Welfare, Japan [10].

Gene context of Moyamoya Disease

• We conclude that coagulopathy like PC or PS deficiency should be considered in children presenting with moyamoya syndrome [11].
• Platelet factor 4 and beta thromboglobulin in Moya-Moya disease [9].
• These differ however from the true moyamoya disease in a number of aspects: the arterial occlusion is unilateral, the evolution is favorable and revascularization does not occur through the peculiar abnormal vessels of the moyamoya syndrome [12].
• Moyamoya syndrome with unusual angiographic findings and protein C deficiency: review of the literature [13].
• Systemic lupus erythematosus associated with moyamoya syndrome [14].

References