Gene Review:
PPBP - pro-platelet basic protein (chemokine (C-X...
Homo sapiens
Synonyms:
B-TG1, Beta-TG, C-X-C motif chemokine 7, CTAP-III, CTAP3, ...
Schiemann,
Grimm,
Hoch,
Gross,
Lindner,
Petersen,
Bulfone-Paus,
Brandt,
Carter,
Catto,
Bamford,
Grant,
Kowal-Bielecka,
Kowal,
Lewszuk,
Bodzenta-Lukaszyk,
Walecki,
Sierakowski,
Hull,
Rowlands,
Lockhart,
Sharland,
Moore,
Hanchard,
Kwiatkowski,
- Presence of autoantibodies to interleukin-8 or neutrophil-activating peptide-2 in patients with heparin-associated thrombocytopenia. Amiral, J., Marfaing-Koka, A., Wolf, M., Alessi, M.C., Tardy, B., Boyer-Neumann, C., Vissac, A.M., Fressinaud, E., Poncz, M., Meyer, D. Blood (1996)
- The melanoma growth stimulatory activity receptor consists of two proteins. Ligand binding results in enhanced tyrosine phosphorylation. Cheng, Q.C., Han, J.H., Thomas, H.G., Balentien, E., Richmond, A. J. Immunol. (1992)
- Beta thromboglobulin and platelet factor 4 in bronchoalveolar lavage fluid of patients with systemic sclerosis. Kowal-Bielecka, O., Kowal, K., Lewszuk, A., Bodzenta-Lukaszyk, A., Walecki, J., Sierakowski, S. Ann. Rheum. Dis. (2005)
- A novel cleavage product of beta-thromboglobulin formed in cultures of stimulated mononuclear cells activates human neutrophils. Walz, A., Baggiolini, M. Biochem. Biophys. Res. Commun. (1989)
- Platelet activation and secretion associated with emotional stress. Levine, S.P., Towell, B.L., Suarez, A.M., Knieriem, L.K., Harris, M.M., George, J.N. Circulation (1985)
- Decreased brain-derived neurotrophic factor (BDNF)- and beta-thromboglobulin (beta-TG)- blood levels in Alzheimer's disease. Laske, C., Stransky, E., Leyhe, T., Eschweiler, G.W., Schott, K., Langer, H., Gawaz, M. Thromb. Haemost. (2006)
- Impact of smoking, physical training and weight reduction on FVII, PAI-1 and hemostatic markers in sedentary men. Gris, J.C., Schved, J.F., Feugeas, O., Aguilar-Martinez, P., Arnaud, A., Sanchez, N., Sarlat, C. Thromb. Haemost. (1990)
- Occurrence of psychosis in patients with epilepsy randomized to tiagabine or placebo treatment. Sackellares, J.C., Krauss, G., Sommerville, K.W., Deaton, R. Epilepsia (2002)
- Beta thromboglobulin and alcohol consumption. Gravett, P.J., Milligan, S.J. Journal of the Royal Army Medical Corps. (1984)
- Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway. Rouault, J.P., Falette, N., Guéhenneux, F., Guillot, C., Rimokh, R., Wang, Q., Berthet, C., Moyret-Lalle, C., Savatier, P., Pain, B., Shaw, P., Berger, R., Samarut, J., Magaud, J.P., Ozturk, M., Samarut, C., Puisieux, A. Nat. Genet. (1996)
- A prospective study of platelets and plasma proteolytic systems during the early stages of Rocky Mountain spotted fever. Rao, A.K., Schapira, M., Clements, M.L., Niewiarowski, S., Budzynski, A.Z., Schmaier, A.H., Harpel, P.C., Blackwelder, W.C., Scherrer, J.R., Sobel, E. N. Engl. J. Med. (1988)
- Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein. Sugano, S., Stoeckle, M.Y., Hanafusa, H. Cell (1987)
- A significant part of macrophage-derived growth factor consists of at least two forms of PDGF. Shimokado, K., Raines, E.W., Madtes, D.K., Barrett, T.B., Benditt, E.P., Ross, R. Cell (1985)
- Platelet activation in muscle contraction headache and migraine. Takeshima, T., Shimomura, T., Takahashi, K. Cephalalgia : an international journal of headache. (1987)
- Secreted platelet proteins with antiheparin and mitogenic activities in chronic renal failure. Guzzo, J., Niewiarowski, S., Musial, J., Bastl, C., Grossman, R.A., Rao, A.K., Berman, I., Paul, D. J. Lab. Clin. Med. (1980)
- beta-thromboglobulin (beta-TG) and platelet factor 4 (PF4) in obstetrical cases. Arocha-Piñango, C.L., Ojeda, A., López, G., García, L., Linares, J. Acta obstetricia et gynecologica Scandinavica. (1985)
- Beta-thromboglobulin and platelet factor 4 in polycythemia patients treated by ticlopidine. Najean, Y., Poirier, O. Acta Haematol. (1984)
- Platelet GP IIIa PlA and GP Ib variable number tandem repeat polymorphisms and markers of platelet activation in acute stroke. Carter, A.M., Catto, A.J., Bamford, J.M., Grant, P.J. Arterioscler. Thromb. Vasc. Biol. (1998)
- Haplotype mapping of the bronchiolitis susceptibility locus near IL8. Hull, J., Rowlands, K., Lockhart, E., Sharland, M., Moore, C., Hanchard, N., Kwiatkowski, D.P. Hum. Genet. (2004)
- Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils. Walz, A., Dewald, B., von Tscharner, V., Baggiolini, M. J. Exp. Med. (1989)
- Different functions for the interleukin 8 receptors (IL-8R) of human neutrophil leukocytes: NADPH oxidase and phospholipase D are activated through IL-8R1 but not IL-8R2. Jones, S.A., Wolf, M., Qin, S., Mackay, C.R., Baggiolini, M. Proc. Natl. Acad. Sci. U.S.A. (1996)
- Down-regulation of neutrophil functions by the ELR(+) CXC chemokine platelet basic protein. Ehlert, J.E., Ludwig, A., Grimm, T.A., Lindner, B., Flad, H.D., Brandt, E. Blood (2000)
- Chemokine regulation of human megakaryocytopoiesis. Gewirtz, A.M., Zhang, J., Ratajczak, J., Ratajczak, M., Park, K.S., Li, C., Yan, Z., Poncz, M. Blood (1995)
- Generation of the neutrophil-activating peptide NAP-2 from platelet basic protein or connective tissue-activating peptide III through monocyte proteases. Walz, A., Baggiolini, M. J. Exp. Med. (1990)
- Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counterregulation by PF-4 through inhibition of chymase and cathepsin G. Schiemann, F., Grimm, T.A., Hoch, J., Gross, R., Lindner, B., Petersen, F., Bulfone-Paus, S., Brandt, E. Blood (2006)
- Purification of two heparin-binding proteins from porcine platelets and their homology with human secreted platelet proteins. Rucinski, B., Poggi, A., James, P., Holt, J.C., Niewiarowski, S. Blood (1983)
- The neutrophil-activating proteins interleukin 8 and beta-thromboglobulin: in vitro and in vivo comparison of NH2-terminally processed forms. Van Damme, J., Rampart, M., Conings, R., Decock, B., Van Osselaer, N., Willems, J., Billiau, A. Eur. J. Immunol. (1990)
- IL-8 and NAP-2 differ in their capacities to bind and chemoattract 293 cells transfected with either IL-8 receptor type A or type B. Ben-Baruch, A., Bengali, K., Tani, K., Xu, L., Oppenheim, J.J., Wang, J.M. Cytokine (1997)
- The differential ability of IL-8 and neutrophil-activating peptide-2 to induce attenuation of chemotaxis is mediated by their divergent capabilities to phosphorylate CXCR2 (IL-8 receptor B). Ben-Baruch, A., Grimm, M., Bengali, K., Evans, G.A., Chertov, O., Wang, J.M., Howard, O.M., Mukaida, N., Matsushima, K., Oppenheim, J.J. J. Immunol. (1997)
- Neutrophils can generate their activator neutrophil-activating peptide 2 by proteolytic cleavage of platelet-derived connective tissue-activating peptide III. Brandt, E., Van Damme, J., Flad, H.D. Cytokine (1991)
- The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2. Ludwig, A., Petersen, F., Zahn, S., Götze, O., Schröder, J.M., Flad, H.D., Brandt, E. Blood (1997)
- Structure and bioactivity of recombinant human CTAP-III and NAP-2. Proudfoot, A.E., Peitsch, M.C., Power, C.A., Allet, B., Mermod, J.J., Bacon, K., Wells, T.N. J. Protein Chem. (1997)
- Differential and additive effects of platelet-derived chemokines on monocyte arrest on inflamed endothelium under flow conditions. Baltus, T., von Hundelshausen, P., Mause, S.F., Buhre, W., Rossaint, R., Weber, C. J. Leukoc. Biol. (2005)
- Lipopolysaccharide-stimulated human monocytes secrete, apart from neutrophil-activating peptide 1/interleukin 8, a second neutrophil-activating protein. NH2-terminal amino acid sequence identity with melanoma growth stimulatory activity. Schröder, J.M., Persoon, N.L., Christophers, E. J. Exp. Med. (1990)
- High- and low-affinity binding of GRO alpha and neutrophil-activating peptide 2 to interleukin 8 receptors on human neutrophils. Schumacher, C., Clark-Lewis, I., Baggiolini, M., Moser, B. Proc. Natl. Acad. Sci. U.S.A. (1992)
- RANTES- and interleukin-8-induced responses in normal human eosinophils: effects of priming with interleukin-5. Schweizer, R.C., Welmers, B.A., Raaijmakers, J.A., Zanen, P., Lammers, J.W., Koenderman, L. Blood (1994)
- The N terminus of interleukin-8 (IL-8) receptor confers high affinity binding to human IL-8. Suzuki, H., Prado, G.N., Wilkinson, N., Navarro, J. J. Biol. Chem. (1994)
- Increased microvascular permeability in vivo in response to intradermal injection of neutrophil-activating protein (NAP-2) in rabbit skin. Van Osselaer, N., Van Damme, J., Rampart, M., Herman, A.G. Am. J. Pathol. (1991)
- Specific CXC but not CC chemokines cause elevated monocyte migration in COPD: a role for CXCR2. Traves, S.L., Smith, S.J., Barnes, P.J., Donnelly, L.E. J. Leukoc. Biol. (2004)
- Immunological localisation of beta-thromboglobulin and platelet factor 4 in human megakaryocytes and platelets. McLaren, K.M., Pepper, D.S. J. Clin. Pathol. (1982)