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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Modifying factors related to asymmetric diabetic retinopathy.

PURPOSE: To identify the modifying factors related to the development of proliferative diabetic retinopathy (PDR). METHODS: Thirty-eight eyes of 19 non-insulin-dependent diabetes mellitus (NIDDM) patients with maintained asymmetric PDR were retrospectively reviewed. RESULTS: Five patients with ipsilateral carotid stenoses > or = 90% had PDR. Four patients with high myopia over 6 dioptres and 4 patients with optic atrophy and at least a quadrant defect in the visual field had non-proliferative diabetic retinopathy. Of 6 patients with unilateral asteroid hyalosis, 5 had no posterior vitreous detachment (PVD) and PDR. CONCLUSION: Two factors reached statistical significance as factors modifying PDR: carotid occlusive disease and PVD. Optic atrophy and high myopia showed trends of being a protective influence.[1]


  1. Modifying factors related to asymmetric diabetic retinopathy. Dogru, M., Inoue, M., Nakamura, M., Yamamoto, M. Eye (London, England) (1998) [Pubmed]
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