The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Exposure to low irradiances favors the synthesis of 9-cis beta, beta-carotene in Dunaliella salina (Teod.).

We examined the effect of irradiance on the synthesis of beta-carotene and its isomers by Dunaliella salina. Growth irradiance had a marked effect both on growth of the alga (which was suppressed at both low and high irradiances) and on the accumulation of beta-carotene. The accumulation of beta-carotene but not alpha-carotene was closely linked to an increase in irradiance. Growth at low irradiances (20-50 micromol m(-2) s(-1)) promoted a high ratio of 9-cis to all-trans beta-carotene (>2:1), while exposure to high irradiances (200-1,250 micromol m(-2) s(-1)) resulted in a large reduction in this ratio (to <0.45:1). A similar pattern was seen for the geometric isomers of alpha-carotene, with exposure to low irradiance favoring the accumulation of the 9-cis form. The carotenoid biosynthesis inhibitors 4-chloro-5(methylamino)-2-(alpha-alpha-alpha-trifluoro-m-tolyl)-3-(sH )-pyridazinone and 2-(4-chlorophenylthio)triethylamine caused the accumulation of the precursors phytoene and lycopene, respectively, in D. salina. High-performance liquid chromatography and infrared analysis showed that phytoene adopted the 15-cis and all-trans forms (as in higher plants), and that lycopene primarily adopted the all-trans form. This indicates that isomerization of beta-carotene takes place during or after cyclization.[1]


WikiGenes - Universities