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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Arthrogryposis multiplex congenita and bilateral mid-brain infarction following maternal overdose of co-proxamol.

We report a case of arthrogryposis multiplex congenita secondary to fetal hypokinesia in a 41-week gestation infant following antenatal central nervous system injury. The mother's pregnancy was complicated by an episode of attempted self harm, with an overdose of co-proxamol at 22 weeks of gestational age, and by the use of cocaine in combination with excess alcohol intake. Magnetic resonance imaging showed bilateral mid-brain cysts and marked atrophy of the basal ganglia and thalami.[1]

References

  1. Arthrogryposis multiplex congenita and bilateral mid-brain infarction following maternal overdose of co-proxamol. Maalouf, E.F., Battin, M., Counsell, S.J., Rutherford, M.A., Manzur, A.Y. Eur. J. Paediatr. Neurol. (1997) [Pubmed]
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