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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Transvenous sclerotherapy for huge oesophagogastric varices using open injection sclerotherapy.

BACKGROUND: The optimum procedure for long-term management of oesophagogastric varices when endoscopic sclerotherapy or ligation fails is yet to be established. This report describes a new procedure for treating huge oesophagogastric varices by open injection sclerotherapy. METHODS: Twenty-three patients with huge oesophagogastric varices underwent laparotomy and devascularization of the upper stomach with splenectomy. The left gastric vein was catheterized for repeated injection of 5 per cent ethanolamine oleate during the postoperative period. RESULTS: In all patients, the varices were eradicated after a mean of 3 sessions of sclerotherapy. There were no deaths or major complications during the mean follow-up period of 41 months. Small recurring varices in two patients were treated successfully by endoscopic sclerotherapy and interventional radiology. CONCLUSION: Open injection sclerotherapy is an effective and safe procedure for the treatment of huge oesophagogastric varices.[1]


  1. Transvenous sclerotherapy for huge oesophagogastric varices using open injection sclerotherapy. Kitano, S., Baatar, D., Bandoh, T., Yoshida, T., Tsuboi, S., Matsumoto, T. The British journal of surgery. (2000) [Pubmed]
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