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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Expression of microglial response factor-1 in microglia and macrophages following cerebral ischemia in the rat.

Microglial response factor-1 is a newly isolated microglial gene, which encodes a Ca(2+) binding protein MRF-1 expressed in microglia and macrophages. We induced 1 h of focal cerebral ischemia or 10 min of global cerebral ischemia in the rat, and investigated the expression of MRF-1 immunoreactivity following ischemia. MRF-1 was present in resting microglia and was upregulated in response to microglial activation. MRF-1 was localized to all the cells of the mononuclear phagocyte system (microglia, monocytes, and perivascular cells) that appeared in the ischemic brain.[1]

References

  1. Expression of microglial response factor-1 in microglia and macrophages following cerebral ischemia in the rat. Kato, H., Tanaka, S., Oikawa, T., Koike, T., Takahashi, A., Itoyama, Y. Brain Res. (2000) [Pubmed]
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