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Yamamoto, K. et al.

Yamamoto, Fujiyama, Andoh, Bamba, Okabe,

Oxidative stress increases MICA and MICB gene expression in the human colon carcinoma cell line (CaCo-2).

The human major histocompatibility complex class I chain-related A gene (MICA) and the MICB gene are newly identified members of the major histocompatibility complex class I chain-related gene family. We demonstrate here that oxidative stress, induced by H(2)O(2), promoted MICA (2.2-fold) and MICB (3.8-fold) gene expression using the human colon carcinoma cell line (CaCo-2) and semi-quantitative RT-PCR.[1]

References

Oxidative stress increases MICA and MICB gene expression in the human colon carcinoma cell line (CaCo-2). Yamamoto, K., Fujiyama, Y., Andoh, A., Bamba, T., Okabe, H. Biochim. Biophys. Acta (2001) [Pubmed]

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