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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

An alternative therapeutic procedure for sinonasal undifferentiated carcinoma.

We describe two cases of sinonasal undifferentiated carcinoma, a rare and highly aggressive neoplasm of the paranasal sinuses. Case 1 had first been diagnosed as esthesioneuroblastoma, and intra-arterial and systemic chemotherapy and radiotherapy were performed. The tumor became smaller but did not disappear, and the patient died 2 months later. Case 2 received systemic chemotherapy and chemoradiotherapy, with daily venous administration of cisplatin during radiotherapy. The tumor became much smaller but also remained, and the patient died a month later. Although the therapy failed, chemoradiotherapy has some possibility of controlling the disease.[1]


  1. An alternative therapeutic procedure for sinonasal undifferentiated carcinoma. Sakamoto, M., Nakamura, K., Nishimura, S. European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. (2001) [Pubmed]
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