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Jia, X.Q. et al.

Expression of midkine in the cochlea.

Midkine ( MK) is one of a new family of heparin-binding growth factors involved in the regulation of growth and differentiation. We have analyzed expression of MK in the cochlea using ICR mice within 1 day from birth. The expression of MK in the cochlea was confirmed by Western blotting and immunohistochemistry. Anti- MK immunoreactivity was observed in the stria vascularis, spiral prominence, spiral ganglion, and ganglion nerve fibers. These findings suggest that MK plays a role in the development of the cochlea.[1]

References

Expression of midkine in the cochlea. Jia, X.Q., Nakashima, T., Kadomatsu, K., Muramatsu, T. Hear. Res. (2001) [Pubmed]

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