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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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In vitro antianaerobic activity of ertapenem (MK-0826) compared to seven other compounds.

Ertapenem, imipenem, meropenem, ceftriaxone, piperacillin, piperacillin-tazobactam, clindamycin, and metronidazole were agar dilution MIC tested against 431 anaerobes. Imipenem, meropenem, and ertapenem were the most active beta-lactams (MICs at which 50% of the strains are inhibited [MIC(50)s], 0.125 to 0.25 microg/ml; MIC(90)s, 1.0 to 2.0 microg/ml). Time-kill studies revealed that ertapenem at two times the MIC was bactericidal for 9 of 10 strains after 48 h. The kinetics for other beta-lactams were similar to those of ertapenem.[1]

References

  1. In vitro antianaerobic activity of ertapenem (MK-0826) compared to seven other compounds. Hoellman, D.B., Kelly, L.M., Credito, K., Anthony, L., Ednie, L.M., Jacobs, M.R., Appelbaum, P.C. Antimicrob. Agents Chemother. (2002) [Pubmed]
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