The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 
 
 

Secondary erythrocytosis associated with high plasma erythropoietin concentrations in a dog with cecal leiomyosarcoma.

A 14-year-old mixed-breed dog was examined because of severe absolute erythrocytosis (PCV, 70%). Plasma erythropoietin ( EPO) concentration was consistently high, even though results of arterial blood gas analyses were normal. Radiography, ultrasonography, urinalysis, and serum biochemical analyses did not reveal any cardiac, pulmonary, or renal abnormalities that could cause the erythrocytosis, and erythrocytosis secondary to inappropriate EPO secretion was diagnosed. The PCV was maintained at approximately 60% by means of periodic phlebotomy, and the dog died of acute renal failure 2 years later. At necropsy, a cecal leiomyosarcoma was identified. Immunohistochemical staining of sections of the tumor revealed intracellular vacuoles containing EPO, and EPO mRNA was detected in the tumor by use of a reverse transcriptase-polymerase chain reaction assay These results suggested that ectopic production of EPO by a cecal leiomyosarcoma was the cause of erythrocytosis in this dog.[1]

References

  1. Secondary erythrocytosis associated with high plasma erythropoietin concentrations in a dog with cecal leiomyosarcoma. Sato, K., Hikasa, Y., Morita, T., Shimada, A., Ozaki, K., Kagota, K. J. Am. Vet. Med. Assoc. (2002) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities