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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Pre- and postnatal toxicity induced in guinea pigs by N-nitrosomethylurea.

Oral administration of N-nitrosomethylurea at maximally tolerated doses to guinea pigs on alternate days from days 34-58 of pregnancy induced prenatal toxicity, as evidenced by a high frequency of stillbirths and intrauterine growth retardation, and postnatal toxicity, as evidenced by stunting and progressive mortality. Similar administration of N-nitrosomethylurethane at maximally tolerated doses did not induce such toxic effects.[1]

References

  1. Pre- and postnatal toxicity induced in guinea pigs by N-nitrosomethylurea. Hasumi, K., Wilber, J.H., Berkowitz, J., Wilber, R.G., Epstein, S.S. Teratology (1975) [Pubmed]
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