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MeSH Review


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Disease relevance of Stillbirth


High impact information on Stillbirth


Chemical compound and disease context of Stillbirth


Biological context of Stillbirth


Anatomical context of Stillbirth

  • RESULTS: We observed an intense somatostatin positivity in many brainstem nuclei prevalently involved in the respiratory activity (parabrachial/Kölliker-Fuse complex, locus coeruleus, hypoglossus nucleus, dorsal vagus motor nucleus, tractus solitarii nucleus, ambiguus nucleus, reticular formation) in stillbirths [19].
  • Mucin histochemistry was performed on the squamocolumnar junction (Z-line) of the gastroesophageal region of 49 autopsied previable fetuses, stillbirths, infants, and young children, using alcian blue pH 2.5/periodic acid-Schiff (PAS) and alcian blue pH 1.0/PAS stains [20].

Associations of Stillbirth with chemical compounds

  • Toluene treatment did not affect the number of implantations or stillbirths [21].
  • In a case-control study spanning five years' experience at Group Health Cooperative of Puget Sound, we could demonstrate no plausible association between the use of spermicides, oral contraceptives, Bendectin, or antibiotics prior to conception and the occurrence of 73 nontraumatic stillbirths [22].
  • The cocaine-treated group had a significant increase in embryonic resorptions but no significant effects on stillbirths or postnatal mortality [23].
  • There were two early neonatal deaths in the magnesium sulphate group, and three stillbirths in the diazepam group [24].
  • Cases with impaired glucose tolerance had no stillbirths and had a lower perinatal loss than the controls, though this was not statistically significant [25].

Gene context of Stillbirth

  • Is G6PD A- deficiency associated with recurrent stillbirths in The Gambia [26]?
  • Induced abortions were frequently omitted by the husbands (sensitivity, 35.1%), and events such as stillbirths or tubal pregnancies were too few in number to permit meaningful analysis [27].
  • Two stillbirths and 3 neonatal deaths occurred in the positive CST group [28].
  • We wished to determine whether the annual incidence of open NTDs in Nova Scotia, including those in stillbirths and terminated pregnancies, changed after the introduction of either folic acid supplementation or fortification [29].
  • An analysis of women who were ever gravid revealed no statistically significant difference in any adverse pregnancy outcome between RA cases (n = 144) and controls (n = 605) including spontaneous abortions and stillbirths [30].

Analytical, diagnostic and therapeutic context of Stillbirth


  1. Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans. Murdoch, S., Djuric, U., Mazhar, B., Seoud, M., Khan, R., Kuick, R., Bagga, R., Kircheisen, R., Ao, A., Ratti, B., Hanash, S., Rouleau, G.A., Slim, R. Nat. Genet. (2006) [Pubmed]
  2. Protein-energy malnutrition in rats during pregnancy modifies the effects of caffeine on fetal bones. Nakamoto, T., Shaye, R. J. Nutr. (1986) [Pubmed]
  3. Maternal and fetal sequelae of anticoagulation during pregnancy in patients with mechanical heart valve prostheses. Sareli, P., England, M.J., Berk, M.R., Marcus, R.H., Epstein, M., Driscoll, J., Meyer, T., McIntyre, J., van Gelderen, C. Am. J. Cardiol. (1989) [Pubmed]
  4. Prenatal factors in the aetiology of testicular cancer: an epidemiological study of childhood testicular cancer deaths in Great Britain, 1953-73. Swerdlow, A.J., Stiller, C.A., Wilson, L.M. Journal of epidemiology and community health. (1982) [Pubmed]
  5. Effects of prenatal exposure to cocaine or related drugs on rat developmental and neurological indices. Henderson, M.G., McMillen, B.A. Brain Res. Bull. (1990) [Pubmed]
  6. Effect of mebendazole therapy during pregnancy on birth outcome. de Silva, N.R., Sirisena, J.L., Gunasekera, D.P., Ismail, M.M., de Silva, H.J. Lancet (1999) [Pubmed]
  7. Lead and cadmium levels in stillbirths. Bryce-Smith, D., Deshpande, R.R., Hughes, J., Waldron, H.A. Lancet (1977) [Pubmed]
  8. Anticoagulation of pregnant women with mechanical heart valves: a systematic review of the literature. Chan, W.S., Anand, S., Ginsberg, J.S. Arch. Intern. Med. (2000) [Pubmed]
  9. The birth prevalence rates for the skeletal dysplasias. Orioli, I.M., Castilla, E.E., Barbosa-Neto, J.G. J. Med. Genet. (1986) [Pubmed]
  10. Adverse reproductive outcomes among women exposed to low levels of ionizing radiation from diagnostic radiography for adolescent idiopathic scoliosis. Goldberg, M.S., Mayo, N.E., Levy, A.R., Scott, S.C., Poîtras, B. Epidemiology (Cambridge, Mass.) (1998) [Pubmed]
  11. Obstetric cholestasis: current opinions and management. Tan, L.K. Ann. Acad. Med. Singap. (2003) [Pubmed]
  12. The effect of strategic anthelmintic treatment on the breeding performance and survival of ewes naturally infected with gastro-intestinal strongyles and protostrongylids. Pandey, V.S., Cabaret, J., Fikri, A. Ann. Rech. Vet. (1984) [Pubmed]
  13. Association of congenital diaphragmatic hernia with limb-reduction defects. van Dooren, M.F., Brooks, A.S., Tibboel, D., Torfs, C.P. Birth defects research. Part A, Clinical and molecular teratology. (2003) [Pubmed]
  14. Analysis of birthweight and gestational age in antepartum stillbirths. Gardosi, J., Mul, T., Mongelli, M., Fagan, D. British journal of obstetrics and gynaecology. (1998) [Pubmed]
  15. Pregnancy outcome in women with prosthetic heart valves. Nassar, A.H., Hobeika, E.M., Abd Essamad, H.M., Taher, A., Khalil, A.M., Usta, I.M. Am. J. Obstet. Gynecol. (2004) [Pubmed]
  16. Effects of prenatal styrene exposure on postnatal development and brain serotonin and catecholamine levels in rats. Katakura, Y., Kishi, R., Ikeda, T., Miyake, H. Environmental research. (2001) [Pubmed]
  17. Effects of parasympathominetics on porcine stillbirth. Sprecher, D.J., Leman, A.D., Carlisle, S. Am. J. Vet. Res. (1975) [Pubmed]
  18. Umbilical cord mannan-binding lectin and infections in early childhood. Kielgast, S., Thiel, S., Henriksen, T.B., Bjerke, T., Olsen, J., Jensenius, J.C. Scand. J. Immunol. (2003) [Pubmed]
  19. Role of somatostatin and apoptosis in breathing control in sudden perinatal and infant unexplained death. Lavezzi, A.M., Ottaviani, G., Matturri, L. Clin. Neuropathol. (2004) [Pubmed]
  20. Mucin histochemistry of the developing gastroesophageal junction. Ellison, E., Hassall, E., Dimmick, J.E. Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association. (1996) [Pubmed]
  21. The effects of high-dose toluene on embryonic development in the rat. Gospe, S.M., Saeed, D.B., Zhou, S.S., Zeman, F.J. Pediatr. Res. (1994) [Pubmed]
  22. Drugs and stillbirth. Porter, J.B., Hunter-Mitchell, J., Jick, H., Walker, A.M. American journal of public health. (1986) [Pubmed]
  23. Prenatal cocaine exposure in the laboratory mouse: effects on maternal water consumption and offspring outcome. Church, M.W., Rauch, H.C. Neurotoxicology and teratology. (1992) [Pubmed]
  24. Magnesium sulphate versus diazepam in the management of eclampsia: a randomized controlled trial. Crowther, C. British journal of obstetrics and gynaecology. (1990) [Pubmed]
  25. The effect of established and gestational diabetes on pregnancy outcome. Johnstone, F.D., Nasrat, A.A., Prescott, R.J. British journal of obstetrics and gynaecology. (1990) [Pubmed]
  26. Is G6PD A- deficiency associated with recurrent stillbirths in The Gambia? Sirugo, G., Schaefer, E.A., Mendy, A., West, B., Bailey, R., Walraven, G., Sabeti, P., Macciardi, F., Zonta, L.A. Am. J. Med. Genet. A (2004) [Pubmed]
  27. Can men be trusted? A comparison of pregnancy histories reported by husbands and wives. Fikree, F.F., Gray, R.H., Shah, F. Am. J. Epidemiol. (1993) [Pubmed]
  28. Evaluation of the contraction stress test before 33 weeks' gestation. Gabbe, S.G., Freeman, R.D., Goebelsmann, U. Obstetrics and gynecology. (1978) [Pubmed]
  29. Incidence of open neural tube defects in Nova Scotia after folic acid fortification. Persad, V.L., Van den Hof, M.C., Dubé, J.M., Zimmer, P. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. (2002) [Pubmed]
  30. Pregnancy outcome in women with rheumatoid arthritis before disease onset. Nelson, J.L., Voigt, L.F., Koepsell, T.D., Dugowson, C.E., Daling, J.R. J. Rheumatol. (1992) [Pubmed]
  31. Prenatal cocaine exposure in the Long-Evans rat: I. Dose-dependent effects on gestation, mortality, and postnatal maturation. Church, M.W., Overbeck, G.W., Andrzejczak, A.L. Neurotoxicology and teratology. (1990) [Pubmed]
  32. A retrospective study of sporadic bovine abortions, stillbirths, and neonatal abnormalities in Atlantic Canada, from 1990 to 2001. Khodakaram-Tafti, A., Ikede, B.O. Can. Vet. J. (2005) [Pubmed]
  33. The placental RCAS1 expression during stillbirth. Wicherek, L., Klimek, M., Czekierdowski, A., Popiela, T.J., Galazka, K., Tetlak, T., Gilowski, A., Dutsch-Wicherek, M. Reprod. Biol. Endocrinol. (2005) [Pubmed]
  34. The prevalence of toxoplasma antibodies in pregnant Nigerian women and the occurrence of stillbirth and congenital malformation. Onadeko, M.O., Joynson, D.H., Payne, R.A., Francis, J. African journal of medicine and medical sciences. (1996) [Pubmed]
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