The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Micellar catalysis of Diels-Alder reactions: substrate positioning in the micelle.

We have studied the kinetics of the Diels-Alder reactions of cyclopentadiene, sorbyl alcohol, and sorbyltrimethylammonium bromide with a series of N-substituted maleimides in micellar media. Micellar rate constants have been determined and were found to be 20-40 times lower than the respective aqueous rate constants. Nevertheless, it was found that upon addition of sodium dodecyl sulfate the observed rate constants could be enhanced up to a factor of about 4. 5. The low micellar rate constants can be attributed to the relatively apolar (water-poor) region of the micelle, in which the reactions take place. NMR experiments indicate that the reactants usually reside near the alpha- or beta-CH2 groups of the surfactant molecules in the micelle. Comparison of the micellar rate constants with rate constants in water/1-propanol mixtures suggests a concentration of water of 10-15 M in the micellar region where the diene and dienophile react.[1]


WikiGenes - Universities