- NK cells mediate increase of phagocytic activity but not of proinflammatory cytokine (interleukin-6 [IL-6], tumor necrosis factor alpha, and IL-12) production elicited in splenic macrophages by tilorone treatment of mice during acute systemic candidiasis. Gaforio, J.J., Ortega, E., Algarra, I., Serrano, M.J., Alvarez de Cienfuegos, G. Clin. Diagn. Lab. Immunol. (2002)