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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Identification of an Arabidopsis mitochondrial succinate-fumarate translocator.

Complementation of a yeast acr1 mutant carrying a deletion of the succinate/fumarate carrier gene enabled functional identification of a mitochondrial succinate translocator from Arabidopsis thaliana (AtmSFC1). Thus complementation of yeast mutants is applicable also for identification and characterization of organellar transporters. Reverse transcription polymerase chain reaction and promoter-GUS fusion showed expression of AtmSFC1 in 2 day old dark grown seedlings, which declined in cotyledons during further development, consistent with a role in export of fumarate for gluconeogenesis during lipid mobilization at early germination of Arabidopsis seeds. In mature plants, expression was found in developing and germinating pollen, suggesting a role in ethanolic fermentation.[1]

References

  1. Identification of an Arabidopsis mitochondrial succinate-fumarate translocator. Catoni, E., Schwab, R., Hilpert, M., Desimone, M., Schwacke, R., Flügge, U.I., Schumacher, K., Frommer, W.B. FEBS Lett. (2003) [Pubmed]
 
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