- Inhibition of both the apical sodium-dependent bile acid transporter and HMG-CoA reductase markedly enhances the clearance of LDL apoB. Telford, D.E., Edwards, J.Y., Lipson, S.M., Sutherland, B., Barrett, P.H., Burnett, J.R., Krul, E.S., Keller, B.T., Huff, M.W. J. Lipid Res. (2003)