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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Sox15 is up regulated in the embryonic mouse testis.

The mammalian sex determining region on the Y chromosome, SRY, is the founding member of the SOX gene family. SOX genes share a common DNA-binding motif termed the HMG box and have diverse roles in vertebrate embryonic development and tissue differentiation. Sox15 expression was analysed during mouse embryogenesis by whole-mount in situ hybridisation and Real Time RT-PCR. Sox15 was found to be expressed in developing mouse gonads from 11.5 dpc to 13.5 dpc with a peak of expression at 12.5 dpc. Expression was approximately twice as high in the male gonad as in the female gonad.[1]


  1. Sox15 is up regulated in the embryonic mouse testis. Sarraj, M.A., Wilmore, H.P., McClive, P.J., Sinclair, A.H. Gene Expr. Patterns (2003) [Pubmed]
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