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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Syrian hamster proopiomelanocortin cDNA cloning and early seasonal changes in testicular expression.

Beta-endorphin (beta-End) and its precursor, proopiomelanocortin ( POMC), are expressed in testis and beta-End stimulates testosterone secretion locally. We measured POMC expression in Syrian hamster testis following transfer from long days (LDs) to short days (SDs). We used RT-PCR to amplify partial-length hamster POMC cDNA to generate a probe for Northern analysis. We also used rat beta-End antiserum for radioimmunoassay analysis. SD exposure for 2 weeks decreased POMC mRNA and beta-End, but not testis weight or testosterone. We conclude that POMC signaling may play a role in seasonal regulation of testicular function.[1]

References

  1. Syrian hamster proopiomelanocortin cDNA cloning and early seasonal changes in testicular expression. Morgan, C., Thompson, R.C., Watson, S.J., Akil, H. Gen. Comp. Endocrinol. (2003) [Pubmed]
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